Solvent Red 23

Description

Solvent Red 23 is an oil-soluble red azo dye used in cosmetic products in Japan. Cases were reported in hairdressers, who also reacted to PPD and to paminoazobenzene. One case of contact dermatitis was reported in the metal industry.

Chemical properties

reddish brown powder

The Uses of Solvent Red 23

Weakly acidic azo dye. Biological stain.

The Uses of Solvent Red 23

Weakly acidic azo dye. Biological stain. Dyes and metabolites, Environmental Testing.

What are the applications of Application

Sudan III is a lysochrome (fat soluble dye) predominantly used for staining triglycerides in animal tissues (frozen sections)

Definition

ChEBI: A bis(azo) compound that is 2-naphthol substituted at position 1 by a 4-{[(2-methylphenyl)diazenyl]phenyl}diazenyl group. A fat-soluble dye predominantly used for demonstrating triglycerides in frozen sections, but which may also stain some protein bound l pids in paraffin sections.

Preparation

4-(Phenyldiazenyl)benzenamine diazotization, and Naphthalen-2-ol coupling. Note: some goods by 4-(Phenyldiazenyl)benzenamine and 2-Methyl-4-(o-tolyldiazenyl)benzenamine mixture as diazo components and have to.

Contact allergens

Solvent Red 23 is an oil-soluble red azo-dye used in cosmetic products in Japan. Cases were reported in hairdressers, who also reacted to PPD (the molecule is likely to be hydrolyzed into PPD) and to p-aminoazobenzene. One case of contact dermatitis was reported in the metal industry.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by subcutaneous and intrapleural routes. Questionable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise the dye from EtOH, EtOH/water or *benzene/absolute EtOH (1:1). [Beilstein 16 II 75, 16 III 148, 16 IV 248.]

Properties and Applications

yellow red to red. Soluble in ethanol and acetone, soluble in benzene. In concentrated sulfuric acid to blue light green, dilution for blue solution, and a red precipitation.