Solvent Red 23

Synonym(s):Solvent Red 23;Sudan G;Sudan Red BK;Tony Red;1-[4-(Phenylazo)phenylazo]-2-naphthol

CAS NO.：85-86-9
Empirical Formula: C22H16N4O
Molecular Weight: 352.39
MDL number: MFCD00003905
EINECS: 201-638-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-20 11:41:24

What is Solvent Red 23?

Description

Solvent Red 23 is an oil-soluble red azo dye used in cosmetic products in Japan. Cases were reported in hairdressers, who also reacted to PPD and to paminoazobenzene. One case of contact dermatitis was reported in the metal industry.

Chemical properties

reddish brown powder

The Uses of Solvent Red 23

Weakly acidic azo dye. Biological stain.

The Uses of Solvent Red 23

Weakly acidic azo dye. Biological stain. Dyes and metabolites, Environmental Testing.

Definition

ChEBI: A bis(azo) compound that is 2-naphthol substituted at position 1 by a 4-{[(2-methylphenyl)diazenyl]phenyl}diazenyl group. A fat-soluble dye predominantly used for demonstrating triglycerides in frozen sections, but which may also stain some protein bound l pids in paraffin sections.

What are the applications of Application

Sudan III is a lysochrome (fat soluble dye) predominantly used for staining triglycerides in animal tissues (frozen sections)

Preparation

4-(Phenyldiazenyl)benzenamine diazotization, and Naphthalen-2-ol coupling. Note: some goods by 4-(Phenyldiazenyl)benzenamine and 2-Methyl-4-(o-tolyldiazenyl)benzenamine mixture as diazo components and have to.

Contact allergens

Solvent Red 23 is an oil-soluble red azo-dye used in cosmetic products in Japan. Cases were reported in hairdressers, who also reacted to PPD (the molecule is likely to be hydrolyzed into PPD) and to p-aminoazobenzene. One case of contact dermatitis was reported in the metal industry.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by subcutaneous and intrapleural routes. Questionable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Properties and Applications

yellow red to red. Soluble in ethanol and acetone, soluble in benzene. In concentrated sulfuric acid to blue light green, dilution for blue solution, and a red precipitation.

Standard	Light Fastness	Heat-resistant(℃)		water	Sodium Carbonate(5%)	Hydrochloric acid(5%)
		Melting point	Stable
ISO	Good	195	70≥ 120 Sublimation	Insoluble	No change	No change

Purification Methods

Crystallise the dye from EtOH, EtOH/water or *benzene/absolute EtOH (1:1). [Beilstein 16 II 75, 16 III 148, 16 IV 248.]

Properties of Solvent Red 23

Melting point:	199 °C (dec.)(lit.)
Boiling point:	486.01°C (rough estimate)
Density	1.2266 (rough estimate)
refractive index	1.6620 (estimate)
storage temp.	Store at +5°C to +30°C.
solubility	Insoluble in water; soluble in benzene, chloroform; moderately soluble in acetone, ether, petroleum ether; slightly soluble in ethanol, xylene
form	Powder
Colour Index	26100
pka	13.45±0.50(Predicted)
color	Red-brown
λmax	507 nm, 354 nm
Merck	14,8884
BRN	2016384
Stability:	Stable. Incompatible with strong oxidizing agents.
Biological Applications	Antiseptic; preventing prostate cancer; medical devices; dental impression materials
CAS DataBase Reference	85-86-9(CAS DataBase Reference)
IARC	3 (Vol. 8, Sup 7) 1987
EPA Substance Registry System	C.I. Solvent Red 23 (85-86-9)

Safety information for Solvent Red 23

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H341:Germ cell mutagenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..…