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solamargine

solamargine Structural

What is solamargine?

Description

First isolated from Solanum marginatum, this alkaloid has also been obtained from the ripe berries of S. khasianum var. chatterjeerum sengupta. It is laevorotatory with [α]20D - 105° (c 0.986, MeOH) and forms a picrate as yellow crystals, m.p. 188-9°C; picrolonate, m.p. 204-SoC and the benzoate with an indefinite melting point. Hydrolysis with 2N methanolic HCl furnishes solasodine, m.p. 197-8°C, one mole of D-glucose and two moles of L-rhamnose.

The Uses of solamargine

Solamargine is a natural steroidal glycoalkaloid produces a mild secondary effect through cortocoids produced in the adrenal glands.

References

Briggs et aI., J. Soc. Chem., 3587 (1952)
Sath., J. [nst. Chem., (Calcutta), 43, 116 (1971)

Properties of solamargine

Melting point: 278-281℃ (dec.) (methanol acetone )
Density  1.42±0.1 g/cm3 (20 ºC 760 Torr)
form  Solid
pka 12.78±0.70(Predicted)
color  White to off-white

Safety information for solamargine

Computed Descriptors for solamargine

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