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HomeProduct name listSodium levothyroxine pentahydrate

Sodium levothyroxine pentahydrate

Synonym(s):3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt;Sodium levothyroxine;T4

  • CAS NO.:6106-07-6
  • Empirical Formula: C15H20I4NNaO9
  • Molecular Weight: 888.93
  • MDL number: MFCD00149110
  • EINECS: 682-494-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-09-10 19:09:04
Sodium levothyroxine pentahydrate Structural

What is Sodium levothyroxine pentahydrate?

What are the applications of Application

L-Thyroxine Sodium Salt Pentahydrate is a thyroid hormone

Hazard

A reproductive hazard.

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Purification Methods

Crystallise the sodium salt from absolute EtOH and dry it for 8hours at 30o/1mm. [Canepa Acta Cryst 4 283 1951, Beilstein 14 II 378, 14 III 1566, 14 IV 2374.]

Properties of Sodium levothyroxine pentahydrate

Melting point: 207-210 (dec.)(lit.)
alpha  [α]D20 +15~+19°
Density  2.381
storage temp.  2-8°C
solubility  cell culture medium: 0.1 mg/mL
form  powder
color  White to Yellow to Orange
BRN  5721845
CAS DataBase Reference 6106-07-6(CAS DataBase Reference)

Safety information for Sodium levothyroxine pentahydrate

Signal word Danger
Pictogram(s)
ghs
Health Hazard
GHS08
GHS Hazard Statements H372:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P314:Get medical advice/attention if you feel unwell.
P501:Dispose of contents/container to..…

Computed Descriptors for Sodium levothyroxine pentahydrate

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