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HomeProduct name listSKF 83959 HYDROBROMIDE

SKF 83959 HYDROBROMIDE

Synonym(s):6-Chloro-7,8-dihydroxy-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

SKF 83959 HYDROBROMIDE Structural

What is SKF 83959 HYDROBROMIDE?

Definition

ChEBI: A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a 3-methylphenyl substituent at position 1, a methyl substituent at position 3, a chloro substituent at position 6 and two hydroxy substituents at positions 7 and 8. Dopamine D1-like receptor p rtial agonist (Ki values are 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively). May act as an antagonist in vivo, producing anti-Parkinsonian effects and antagonising the behavioral effects of cocaine.

Biological Activity

Dopamine D 1 -like receptor partial agonist (K i values are 1.18, 7.56, 920 and 399 nM for rat D 1 , D 5 , D 2 and D 3 receptors respectively). May act as an antagonist in vivo , producing antiparkinsonian effects and antagonizing the behavioral effects of cocaine.

Properties of SKF 83959 HYDROBROMIDE

storage temp.  Store at RT
solubility  DMSO: 26 mg/mL, soluble
form  solid
color  white

Safety information for SKF 83959 HYDROBROMIDE

Computed Descriptors for SKF 83959 HYDROBROMIDE

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