SKF 83959 HYDROBROMIDE
Synonym(s):6-Chloro-7,8-dihydroxy-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
- CAS NO.:80751-85-5
- Empirical Formula: C18H20ClNO2
- Molecular Weight: 317.81
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-09 19:38:33
What is SKF 83959 HYDROBROMIDE?
Definition
ChEBI: A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a 3-methylphenyl substituent at position 1, a methyl substituent at position 3, a chloro substituent at position 6 and two hydroxy substituents at positions 7 and 8. Dopamine D1-like receptor p rtial agonist (Ki values are 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively). May act as an antagonist in vivo, producing anti-Parkinsonian effects and antagonising the behavioral effects of cocaine.
Biological Activity
Dopamine D 1 -like receptor partial agonist (K i values are 1.18, 7.56, 920 and 399 nM for rat D 1 , D 5 , D 2 and D 3 receptors respectively). May act as an antagonist in vivo , producing antiparkinsonian effects and antagonizing the behavioral effects of cocaine.
Properties of SKF 83959 HYDROBROMIDE
storage temp. | Store at RT |
solubility | DMSO: 26 mg/mL, soluble |
form | solid |
color | white |
Safety information for SKF 83959 HYDROBROMIDE
Computed Descriptors for SKF 83959 HYDROBROMIDE
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION XANTHAN GUM Racecadotril SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN Folic Acid Impurity G Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid Salt Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
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