SITS
Synonym(s):Disodium 4-acetamido-4′-isothiocyanato-stilben-2,2′-disulfonate;SITS
- CAS NO.:51023-76-8
- Empirical Formula: C17H12N2Na2O7S3
- Molecular Weight: 498.46
- MDL number: MFCD00007485
- EINECS: 256-919-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:20
What is SITS?
Chemical properties
Light Yellow Solid
The Uses of SITS
A fluorescent label for the specific and reversible labelling of the outer components of the plasma membrane. The reagent reacts with a fixed number of sites on the surface of cells concerned with anion permeation; does not pass through the osmotic barrier of the membrane; reacts under physiological conditions of temperature, pH and tonicity; and is detectable in small amounts. SEE ALSO NOTES FOR DIDS (CAT#D460600). Fluorescence: max. Abs. l = 336nm, max. Em. l = 436 nm.
The Uses of SITS
Fluorescent marker for membranes; inhibits anion permeability of membranes. Also inactivates Na,K-ATPase, by covalent modification of a specific Lys residue.
Properties of SITS
Melting point: | >300°C (dec.) |
storage temp. | -20°C |
solubility | Soluble in water, methanol, dimethyl
sulfoxide |
form | powder |
color | Yellow or tan-yellow |
λmax | 336 nm |
BRN | 9177451 |
Stability: | Temperature sensitive - recommended storage at -20oC |
Biological Applications | Chloride channel blockers; anion transport inhibitors; treating cancer,glaucoma,heart diseases,viral diseases |
CAS DataBase Reference | 51023-76-8(CAS DataBase Reference) |
EPA Substance Registry System | Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, disodium salt (51023-76-8) |
Safety information for SITS
Signal word | Danger |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Health Hazard GHS08 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for SITS
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
4-Vinylanilin
4-AMINOSTILBENE
TRANS-4-ACETYL-AMINOSTILBENE
N-(4-VINYL-PHENYL)-ACETAMIDE
4,4'-DIAMINOSTILBENE DIHYDROCHLORIDE
4-METHYLFORMANILIDE
TRANS-STILBENE
4-Methylphenyl isothiocyanate
You may like
-
4-Acetamido-4′-isothiocyanato-2,2′-stilbenedisulfonic acid disodium salt hydrate CAS 51023-76-8View Details
51023-76-8 -
1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%View Details
99903-60-3 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.