segetalin B
- CAS NO.:164991-89-3
- Empirical Formula: C24H32N6O5
- Molecular Weight: 484.55
- MDL number: MFCD30725502
- Update Date: 2024-11-19 20:33:22
What is segetalin B?
Description
Segetalin B, a cyclopentapeptide from Vaccaria segetalis, possesses estrogen-like activity.
Physical properties
Cyclic pentapeptide. Constit. of the seeds of Vaccaria segetalis (Caryophyllaceae).Needles.Mp 153-155°C.
Pharmacology
Examples of naturally occurring bioactive cyclopeptides are Segetalins A and B,which were isolated from Vaccaria segetalis (Caryophyllacea) and were shown to have estrogen-like activity. The seeds of Vaccaria segetalis are used in Chinese folk medicine to activate blood flow, to promote milk secretion, and to treat amenorrhea and breast infections. That Segetalin A and Segetalin B have the Try-Ala-Gly-Val (WAGV) sequence in common indicates this is the biologically active part of the molecules. NMR studies indicate,however,that the orientation of the Val residue is different in the molecules.The effect of this amino acid on the activity of the compounds might not be very important.
Properties of segetalin B
Boiling point: | 999.4±65.0 °C(Predicted) |
Density | 1.177±0.06 g/cm3(Predicted) |
solubility | DMSO : 250 mg/mL (515.94 mM; Need ultrasonic) |
pka | 13.35±0.70(Predicted) |
form | Solid |
color | White to off-white |
Safety information for segetalin B
Computed Descriptors for segetalin B
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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