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HomeProduct name listSE 175

SE 175

SE 175 Structural

What is SE 175?

Description

SE 175 is an organic nitrate compound of the same general class as nitroglycerin. These nitrate compounds can act as NO-donors in vivo following reductive transformation of the nitrate group to nitric oxide. The nitroxyacylated thiosalicylates, such as SE 175, were developed in an effort to facilitate this reductive process and accelerate the release of NO. SE 175 is stable in buffer or saline solution. In the intact rat, it stimulates endothelial soluble guanylate cyclase and induces aortic vasorelaxation with an EC50 of 20 μM, which is intermediate in potency between nitroglycerine and isosorbide dinitrate.

What are the applications of Application

SE 175 is a potential NO donor

Properties of SE 175

Boiling point: 493.8±45.0 °C(Predicted)
Density  1.40±0.1 g/cm3(Predicted)
storage temp.  −20°C
solubility  DMF:50.0(Max Conc. mg/mL);143.53(Max Conc. mM)
DMSO:35.0(Max Conc. mg/mL);100.47(Max Conc. mM)
Ethanol:11.0(Max Conc. mg/mL);31.58(Max Conc. mM)
form  A crystalline solid

Safety information for SE 175

Computed Descriptors for SE 175

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