SB 205384
Synonym(s):4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester
- CAS NO.：160296-13-9
- Empirical Formula: C17H18N2O3S
- Molecular Weight: 330.4
- MDL number: MFCD00918851
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:08
What is SB 205384?
The Uses of SB 205384
SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity.
What are the applications of Application
SB 205384 is a GABAA receptor modulator
Definition
ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine.
Biological Activity
GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits.
Properties of SB 205384
| Boiling point: | 565.3±50.0 °C(Predicted) |
| Density | 1.380±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | DMSO: 18 mg/mL |
| form | solid |
| pka | 14.28±0.20(Predicted) |
| color | off-white |
Safety information for SB 205384
Computed Descriptors for SB 205384
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER](https://img.chemicalbook.in/CAS/GIF/21344-30-9.gif)
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