SB 205384
Synonym(s):4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester
- CAS NO.：160296-13-9
- Empirical Formula: C17H18N2O3S
- Molecular Weight: 330.4
- MDL number: MFCD00918851
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is SB 205384?
The Uses of SB 205384
SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity.
What are the applications of Application
SB 205384 is a GABAA receptor modulator
Definition
ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine.
Biological Activity
GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits.
Properties of SB 205384
| Boiling point: | 565.3±50.0 °C(Predicted) |
| Density | 1.380±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | DMSO: 18 mg/mL |
| form | solid |
| pka | 14.28±0.20(Predicted) |
| color | off-white |
Safety information for SB 205384
Computed Descriptors for SB 205384
New Products
4,4-Difluoropiperidine hydrochloride tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Indole Methyl Resin N-Isopropylurea N,N-Dicyclohexylcarbodiimide(DCC) MELDRUMS ACID 5-METHYLISOXAZOLE-4-CARBOXYLIC ACID Magnessium Bis glycinate Zinc ascorbate 1-bromo-2-butyne 2-acetamidophenol 9(10H)-anthracenone Erythrosin B, 4-Piperidinopiperidine 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 2-(benzylamino)acetic acid hydrochloride 4-(tert-Butoxycarbonylamino)but- 2-ynoic acid 3,4-dihydro-2H-benzo[b][1,4]dioxepine 1-Phenyl-1-cycloprppanecarboxylicacidRelated products of tetrahydrofuran
![THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER](https://img.chemicalbook.in/CAS/GIF/21344-30-9.gif)
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