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HomeProduct name listSB 205384

SB 205384

Synonym(s):4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester

SB 205384 Structural

What is SB 205384?

The Uses of SB 205384

SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity.

What are the applications of Application

SB 205384 is a GABAA receptor modulator

Definition

ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine.

Biological Activity

GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits.

Properties of SB 205384

Boiling point: 565.3±50.0 °C(Predicted)
Density  1.380±0.06 g/cm3(Predicted)
storage temp.  Desiccate at RT
solubility  DMSO: 18 mg/mL
form  solid
pka 14.28±0.20(Predicted)
color  off-white

Safety information for SB 205384

Computed Descriptors for SB 205384

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