SB 205384
Synonym(s):4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester
- CAS NO.:160296-13-9
- Empirical Formula: C17H18N2O3S
- Molecular Weight: 330.4
- MDL number: MFCD00918851
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:08
What is SB 205384?
The Uses of SB 205384
SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity.
What are the applications of Application
SB 205384 is a GABAA receptor modulator
Definition
ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine.
Biological Activity
GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits.
Properties of SB 205384
Boiling point: | 565.3±50.0 °C(Predicted) |
Density | 1.380±0.06 g/cm3(Predicted) |
storage temp. | Desiccate at RT |
solubility | DMSO: 18 mg/mL |
form | solid |
pka | 14.28±0.20(Predicted) |
color | off-white |
Safety information for SB 205384
Computed Descriptors for SB 205384
New Products
Tubulysin F 2,2-diethoxyethanethioamide Tubulysin D Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 4,4-DIFLUOROPIPERIDINE 2H-Pyran, 4-ethynyltetrahydro- 4-(Benzyloxy)-3-bromophenylacetic Acid 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 2,2-Difluoropropanol (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Imeglimin Hydrochloride IH Magnesium Trisilicate Latanoprostene Bunod Lubiprostone Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
2-BUTYNYL ACETATE
4-AMINO-3-FORMYLPYRIDINE
(4-AMINO-PYRIDIN-3-YL)-METHANOL
Methyl 4-aminopyridine-3-carboxylate
4-Amino-3-pyridinecarboxylic acid
THIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID METHYL ESTER
PROP-2-YNYL NICOTINATE
SB 205384
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