Salmeterol xinafoate
Synonym(s):(±) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol xinafoate;GR 33343X xinafoate;Salmeterol xinafoate
- CAS NO.：94749-08-3
- Empirical Formula: C36H45NO7
- Molecular Weight: 603.74
- MDL number: MFCD00897708
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-11-20 12:07:38
What is Salmeterol xinafoate?
Description
Salmeterol xinafoate is a new long-acting β2-selective adrenoceptor agonist introduced as a bronchodilator for the treatment of reversible airway obstruction in asthma and chronic bronchitis. It has bronchodilatory activity as intense and four times longerlasting than equivalent doses of salbutamol. It is reported to be the first bronchodilator with significant anti-inflammatory activity and hence could complement prophylactic corticosteroid therapy.
Chemical properties
White to Off-White Solid
Originator
Glaxo (United Kingdom)
The Uses of Salmeterol xinafoate
Salmeterol xinafoate is a β2-Adrenergic agonist.
The Uses of Salmeterol xinafoate
Smooth wheezing anti-inflammatory
Definition
ChEBI: Salmeterol xinafoate is a naphthoic acid.
brand name
Serevent (GlaxoSmithKline).
Biochem/physiol Actions
β2-adrenoceptor agonist.
storage
Desiccate at RT
Properties of Salmeterol xinafoate
| Melting point: | 137-138°C |
| storage temp. | 2-8°C |
| solubility | H2O: slightly soluble |
| form | solid |
| color | white |
| Merck | 14,8337 |
| CAS DataBase Reference | 94749-08-3(CAS DataBase Reference) |
Safety information for Salmeterol xinafoate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Salmeterol xinafoate
| InChIKey | XTZNCVSCVHTPAI-UHFFFAOYSA-N |
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