Salmeterol xinafoate

Synonym(s):(±) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol xinafoate;GR 33343X xinafoate;Salmeterol xinafoate

CAS NO.：94749-08-3
Empirical Formula: C36H45NO7
Molecular Weight: 603.74
MDL number: MFCD00897708
SAFETY DATA SHEET (SDS)
Update Date: 2023-11-20 12:07:38

What is Salmeterol xinafoate?

Description

Salmeterol xinafoate is a new long-acting β2-selective adrenoceptor agonist introduced as a bronchodilator for the treatment of reversible airway obstruction in asthma and chronic bronchitis. It has bronchodilatory activity as intense and four times longerlasting than equivalent doses of salbutamol. It is reported to be the first bronchodilator with significant anti-inflammatory activity and hence could complement prophylactic corticosteroid therapy.

Chemical properties

White to Off-White Solid

Originator

Glaxo (United Kingdom)

The Uses of Salmeterol xinafoate

Salmeterol xinafoate is a β2-Adrenergic agonist.

The Uses of Salmeterol xinafoate

Smooth wheezing anti-inflammatory

Definition

ChEBI: Salmeterol xinafoate is a naphthoic acid.

brand name

Serevent (GlaxoSmithKline).

Biochem/physiol Actions

β2-adrenoceptor agonist.

storage

Desiccate at RT

Properties of Salmeterol xinafoate

Melting point:	137-138°C
storage temp.	2-8°C
solubility	H₂O: slightly soluble
form	solid
color	white
Merck	14,8337
CAS DataBase Reference	94749-08-3(CAS DataBase Reference)

Safety information for Salmeterol xinafoate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.