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HomeProduct name listSALICYLIDENE SALICYLHYDRAZIDE

SALICYLIDENE SALICYLHYDRAZIDE

Synonym(s):2-Hydroxybenzylidene 2-hydroxybenzhydrazide;NSC 87864;SCS

  • CAS NO.:3232-36-8
  • Empirical Formula: C14H12N2O3
  • Molecular Weight: 256.26
  • MDL number: MFCD00043494
  • EINECS: 221-773-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-30 20:13:01
SALICYLIDENE SALICYLHYDRAZIDE Structural

What is SALICYLIDENE SALICYLHYDRAZIDE?

The Uses of SALICYLIDENE SALICYLHYDRAZIDE

SCS is a selective inhibitor of β1-containing GABAA receptors.

What are the applications of Application

SCS is potent and selective partial inhibitor of β1-containing GABAA receptors

Definition

ChEBI: 2-hydroxy-N'-[(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]benzohydrazide is a member of salicylamides.

Biological Activity

Potent and selective partial inhibitor of β 1-containing GABA A receptors (IC 50 values are 4.5, 5.3 and 7.9 nM at α 2 β 1 γ 1 θ , α 2 β 1 γ 1 and α 2 β 1 γ 2s GABA A receptors respectively). May bind allosterically to a novel site on GABA A receptor.

Properties of SALICYLIDENE SALICYLHYDRAZIDE

Melting point: 280-284°C
storage temp.  Store at RT
solubility  DMSO: ~20 mg/mL
form  solid
color  off-white
BRN  2944701
CAS DataBase Reference 3232-36-8(CAS DataBase Reference)
EPA Substance Registry System Benzoic acid, 2-hydroxy-, [(2-hydroxyphenyl)methylene]hydrazide (3232-36-8)

Safety information for SALICYLIDENE SALICYLHYDRAZIDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for SALICYLIDENE SALICYLHYDRAZIDE

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