SACLOFEN
Synonym(s):β-(Aminomethyl)-4-chlorobenzeneethanesulfonic acid
- CAS NO.：125464-42-8
- Empirical Formula: C9H12ClNO3S
- Molecular Weight: 249.71
- MDL number: MFCD00216817
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is SACLOFEN?
The Uses of SACLOFEN
Saclofen is a GABABR antagonist that has been shown to reduced leukocyte migration and increase Fos expression in T7-T11 sympathetic preganglionic neurons
The Uses of SACLOFEN
Saclofen has been used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats.
What are the applications of Application
Saclofen is a selective GABAB antagonist
Definition
ChEBI: 3-amino-2-(4-chlorophenyl)-1-propanesulfonic acid is an organochlorine compound.
Biological Activity
Selective antagonist at GABA B receptors.
Biochem/physiol Actions
Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action.
storage
Room temperature
Properties of SACLOFEN
| Melting point: | 310-315℃ (decomposition) |
| Density | 1.437±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 0.1 M NaOH: 20 mg/mL |
| form | solid |
| pka | 1.15±0.50(Predicted) |
| color | white |
| Water Solubility | Soluble in water (10mM) |
| CAS DataBase Reference | 125464-42-8(CAS DataBase Reference) |
Safety information for SACLOFEN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for SACLOFEN
| InChIKey | JYLNVJYYQQXNEK-UHFFFAOYSA-N |
New Products
4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION Methylcobalamin (vitamin B12) SODIUM METHYL PARABEN SODIUM VALPROATE AMOXICILLIN (AMOXYCILLIN) TRIHYDRATE ACICLOVIRRelated products of tetrahydrofuran
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