S(-)-VERAPAMIL
- CAS NO.：36622-28-3
- Empirical Formula: C27H38N2O4
- Molecular Weight: 454.6
- MDL number: MFCD00869809
- EINECS: 253-132-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:38
What is S(-)-VERAPAMIL?
Chemical properties
White Solid
The Uses of S(-)-VERAPAMIL
Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.
Definition
ChEBI: (S)-verapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of (S)-verapamil and hydrogen chloride. It is an enantiomer of a dexverapamil hydrochloride.
Biochem/physiol Actions
Active enantiomer of (±)-verapamil. Ca2+ channel (L-type) modulator; adrenoceptor antagonist; cardiac depressant.
Properties of S(-)-VERAPAMIL
| Melting point: | 131-133 °C |
| solubility | H2O: >30 mg/mL |
| form | solid |
| color | white |
| optical activity | [α]22/D 6.1°, c = 0.1 in ethanol(lit.) |
Safety information for S(-)-VERAPAMIL
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for S(-)-VERAPAMIL
New Products
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