S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

CAS NO.：5653-80-5
Empirical Formula: C21H27NO
Molecular Weight: 309.45
MDL number: MFCD00151717
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:19

What is S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O?

The Uses of S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

Dextromethadone-D3 is an impurity of Dextromethadone (CAS #: 5653-80-5). Dextromethadone is used in therapy for treating or preventing depression or other mood diseases.

Definition

ChEBI: Dextromethadone is a 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder. It has a role as a NMDA receptor antagonist and an opioid analgesic. It is an enantiomer of a levomethadone.

Properties of S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

Melting point:	100.5°C
Boiling point:	449.71°C (rough estimate)
Density	1.0350 (rough estimate)
refractive index	1.5614 (estimate)
solubility	H₂O: soluble
form	solid
pka	9.05±0.50(Predicted)
color	white

Safety information for S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

Computed Descriptors for S(+)-METHADONE HYDROCHLORIDE INACTIVE EN ANTIOMER O

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