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HomeProduct name list(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE Structural

What is (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE?

Chemical properties

white to light yellow crystal powde

The Uses of (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

(S)-(-)-5-Hydroxymethyl-2(5H)-furanone is used in the preparation of partially saturated heterocycles via a diastereoselective ring chain formation. It is also used in the synthesis of (1R,3S)-cis-chrysanthemic acid.

The Uses of (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

(S)-(?)-5-Hydroxymethyl-2(5H)-furanone can be used as a starting material in the preparation of:

  • Partially saturated heterocycles via a diastereoselective ring chain formation.
  • A natural product named (+)-muscarine.
  • 3′-Ethynylthymidine as a possible antiviral agent.

Properties of (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

Melting point: 41-43 °C(lit.)
Boiling point: 173.58°C (rough estimate)
Density  1.2583 (rough estimate)
refractive index  1.4630 (estimate)
Flash point: >230 °F
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly), Water (Sparingly)
form  Solid
pka 13.51±0.10(Predicted)
color  Off-White Low-Melting
optical activity [α]20/D 144°, c = 1 in H2O
Water Solubility  Slightly soluble in water.
Sensitive  Hygroscopic
BRN  3537455
Stability: Moisture Sensitive
CAS DataBase Reference 78508-96-0(CAS DataBase Reference)

Safety information for (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (S)-(-)HYDROXYMETHYL-3(2H)-FURANONE

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