(S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
Synonym(s):(+)-MCPG;S(+)-α-Amino-4-carboxy-α-methyl-benzeneacetic acid
- CAS NO.:150145-89-4
- Empirical Formula: C10H11NO4
- Molecular Weight: 209.2
- MDL number: MFCD00216858
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-12 17:15:03
What is (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE?
Chemical properties
white to off-white solid
The Uses of (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
Active enantiomer of (±)-MCPG
What are the applications of Application
(S)-MCPG is a non-selective group I/II mGluR antagonist
Definition
ChEBI: (S)-alpha-methyl-4-carboxyphenylglycine is a non-proteinogenic alpha-amino acid that is alanine in which the alpha-hydrogen is replaced by a 4-carboxyphenyl group (the S-enantiomer). It is a non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. It has a role as a metabotropic glutamate receptor antagonist.
Biological Activity
Active isomer of (RS)-MCPG ((RS)-a-Methyl-4-carboxyphenylglycine ). Non-selective group I/group II metabotropic glutamate receptor antagonist. Also available as part of the Group I mGlu Receptor Tocriset™ , Group II mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ .
Biochem/physiol Actions
(+)-α-Methyl-4-carboxyphenylglycine, also known as MCPG, is a competitive metabotropic glutamate receptor antagonist.
storage
Room temperature
Properties of (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
Boiling point: | 425.3±40.0 °C(Predicted) |
Density | 1.390±0.06 g/cm3(Predicted) |
storage temp. | Store at RT |
solubility | 0.1 M NaOH: 15 mg/mL |
form | solid |
pka | 1.76±0.10(Predicted) |
color | White to off-white |
optical activity | [α]20/D +89.54°, c = 0.33 in 6 M HCl(lit.) |
Safety information for (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
Computed Descriptors for (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
New Products
Tubulysin I Tubulysin C (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Potassium HMDS (1.0 M in THF) tetrahydro-4-methyl-2H-pyran 4,4-DIFLUOROPIPERIDINE 4,4-DIFLUOROCYCLOHEXANAMINE 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 2,2-Difluoropropanol 3-Aminocyclobutanone hydrochloride Imeglimin Hydrochloride IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Calcium Sodium Phosphosilicate IH Fuel shell Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
You may like
-
(+)-α-Methyl-4-carboxyphenylglycine CAS 150145-89-4View Details
150145-89-4 -
(R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateView Details
2416850-45-6 -
methyl 3-fluoro-4- thiomorpholino phenylcarbamateView Details
2760359-22-4 -
Fuel shell 98%View Details
-
4,6-dichloro-2-propylthiopyrimidine-5-amine 145783-15-9 98%View Details
145783-15-9 -
151767-02-1 Montelukast Sodium IP/USP 98%View Details
151767-02-1 -
Valacyclovir Hydrochloride IH 98%View Details
124832-27-5 -
2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 98%View Details
142569-70-8