(S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID
- CAS NO.：295325-62-1
- Empirical Formula: C14H17N3O6
- Molecular Weight: 323.3
- MDL number: MFCD06798370
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID?
The Uses of (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID
MNI-caged-L-glutamate, is a new caged neuroactive amino acid, that use 4-methoxy-7-nitroindolinyl- (MNI) group to make caged ligands specific for glutamate receptor sub-types. MNI-caged-L-glutamate, rapidly release glutamate when photolysed.
What are the applications of Application
MNI-caged-L-glutamate is rapidly and efficiently releases glutamate when photolysed with 300 - 380 nm light.
Biological Activity
Caged glutamate that rapidly and efficiently releases glutamate when photolysed (300-380 nm excitation). Water-soluble, highly resistant to hydrolysis, stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). 2.5-fold more efficient at releasing L-glutamate than NI-caged L-glutamate.
storage
-20°C (protect from light)
Properties of (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID
| Melting point: | >160°C (dec.) |
| Boiling point: | 675.1±55.0 °C(Predicted) |
| Density | 1.437±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | 2.20±0.10(Predicted) |
| color | Light Yellow |
| Water Solubility | Soluble to 50 mM in water with gentle warming |
Safety information for (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID
Computed Descriptors for (S)-ALPHA-AMINO-2,3-DIHYDRO-4-METHOXY-7-NITRO-D-OXO-1H-INDOLE-1-PENTANOIC ACID
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