(S)-4-Chloro-3-hydroxybutyronitrile

CAS NO.：127913-44-4
Empirical Formula: C4H6ClNO
Molecular Weight: 119.55
MDL number: MFCD00273363
EINECS: 1308068-626-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-06-12 17:09:27

What is (S)-4-Chloro-3-hydroxybutyronitrile?

Chemical properties

Colorless to light yellow liqui

The Uses of (S)-4-Chloro-3-hydroxybutyronitrile

(3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparat ion of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.

The Uses of (S)-4-Chloro-3-hydroxybutyronitrile

(3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparation of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.

Properties of (S)-4-Chloro-3-hydroxybutyronitrile

Boiling point:	110 °C/1 mmHg(lit.)
Density	1.250 g/mL at 20 °C(lit.)
refractive index	n20/D 1.474(lit.)
Flash point:	110 °C
storage temp.	2-8°C
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Oil
pka	12.67±0.20(Predicted)
color	Clear Colourless
InChI	InChI=1S/C4H6ClNO/c5-3-4(7)1-2-6/h4,7H,1,3H2/t4-/m0/s1
CAS DataBase Reference	127913-44-4(CAS DataBase Reference)