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HomeProduct name list(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester

(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester

  • CAS NO.:177036-78-1
  • Empirical Formula: C17H18O4
  • Molecular Weight: 286.32
  • MDL number: MFCD11865341
  • EINECS: 1533716-785-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester Structural

What is (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester?

The Uses of (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester

(S)-α-Hydroxy-β-methoxy-β-phenyl-benzenepropanoic Acid Methyl Ester is an impurity in the synthesis of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive. (Ambrisentan Hydroxyester Impurity)

Properties of (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester

Melting point: 61-62o C
Boiling point: 440.7±40.0 °C(Predicted)
Density  1.176
storage temp.  2-8°C
solubility  Chloroform (Slightly, Sonicated), DMSO (Slightly)
form  Solid
pka 12.37±0.20(Predicted)
color  White to Off-White
Stability: Hygroscopic

Safety information for (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester

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