(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
- CAS NO.:177036-78-1
- Empirical Formula: C17H18O4
- Molecular Weight: 286.32
- MDL number: MFCD11865341
- EINECS: 1533716-785-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester?
The Uses of (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
(S)-α-Hydroxy-β-methoxy-β-phenyl-benzenepropanoic Acid Methyl Ester is an impurity in the synthesis of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive. (Ambrisentan Hydroxyester Impurity)
Properties of (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
Melting point: | 61-62o C |
Boiling point: | 440.7±40.0 °C(Predicted) |
Density | 1.176 |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly, Sonicated), DMSO (Slightly) |
form | Solid |
pka | 12.37±0.20(Predicted) |
color | White to Off-White |
Stability: | Hygroscopic |
Safety information for (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid methyl ester
New Products
Tubulysin I Tubulysin F Tubulysin B 3-Aminocyclobutanone hydrochloride tetrahydro-4-methyl-2H-pyran 3-METHYLAZETIDIN-3-OL HYDROCHLORIDE 2H-Pyran, 4-ethynyltetrahydro- 4,4-DIFLUOROCYCLOHEXANAMINE 1-(1,1-Difluoroethyl)-2-fluorobenzene 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Imeglimin Hydrochloride IH Fuel shell Calcium Sodium Phosphosilicate IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2,3-dichloro-6- nitrobenzonitrile (+/-)-2, 6-Diamino-4,5,6,7 -tetrahydro Benzothiazole Magnesium Trisilicate Latanoprostene Bunod Lubiprostone Flame Retardant Zinc Borate 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
rac-Ambrisentan-d5
(R)-AMbrisentan
Benzenepropanoic acid,a-hydroxy-b-methoxy-b-phenyl-,(aS)-
Sodium hydrogen difluoride
4-Hydroxy Methyl Ambrisentan-D3
MATFPFPXUXCLHI-UHFFFAOYSA-N
Ambrisentan Acyl Glucuronide (Mixture of Diastereomers)
2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3,3-diphenyl-2-propenoic Acid
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