(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE
Synonym(s):O-Acetyl-L -lactyl chloride;AP-Cl
- CAS NO.：36394-75-9
- Empirical Formula: C5H7ClO3
- Molecular Weight: 150.56
- MDL number: MFCD00145252
- EINECS: 420-610-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:39
What is (S)-(-)-2-ACETOXYPROPIONYL CHLORIDE?
The Uses of (S)-(-)-2-ACETOXYPROPIONYL CHLORIDE
Frequently used chiral building block. Also used to resolve a bicyclic α-hydroxylactone and to prepare chiral phosphonates used in an enantiomeric excess assay of unprotected amino acids. Useful chiral derivatizing agent.
Purification Methods
It is moisture sensitive and is hydrolysed to the corresponding acid. Check the IR spectrum. If the OH band above 3000cm -1 is too large and broad then the mixture should be refluxed with pure acetyl chloride for 1hour, evaporated and distilled under reduced pressure. [Julia & Sans J Chromatographic Sci 17 651 1979, Dolittle & Heath J Org Chem 49 5041 1984, Beilstein 3 II 189.]
Properties of (S)-(-)-2-ACETOXYPROPIONYL CHLORIDE
| Boiling point: | 50 °C5 mm Hg(lit.) |
| alpha | -31o (C=4 IN CHLOROFORM) |
| Density | 1.189 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Sparingly) |
| form | clear liquid |
| Specific Gravity | 1.19 |
| color | Colorless to Light yellow |
| optical activity | [α]20/D 31°, c = 4 in chloroform |
| BRN | 1722943 |
| Stability: | Hygroscopic, Moisture sensitive |
| CAS DataBase Reference | 36394-75-9(CAS DataBase Reference) |
Safety information for (S)-(-)-2-ACETOXYPROPIONYL CHLORIDE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-(-)-2-ACETOXYPROPIONYL CHLORIDE
Abamectin manufacturer
New Products
(R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin M Tubulysin G Tubulysin D 2,2-Difluoropropanol (S)-(+)-3-HYDROXYTETRAHYDROFURAN Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- 3,6-Dihydro-2H-pyran-4-carbonitrile 4-IODOTETRAHYDRO-2H-PYRAN 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 4-N-Methylamino- 3-nitro benzoic acid 1-tosyl-3-(S)-(-)- tosyloxypyrrolidine (3-Fluoro-4- morpholin-4-yl- phenyl)- carbamic acid methyl ester 5-Piperazin-1-yl- benzofuran-2- carboxylic acid ethyl ester. HCl 2-(2-Formylphenoxy) acetic acid (+/-)-6-Acetylamino-2- amino-4, 5, 6, 7-tetrahydro Benzo thiazole 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid (R)-methyl 2-formamido-3-(tritylthio)propanoate (R)-methyl 2-isocyano-3-(tritylthio)propanoate BETAMETHASONE VALERATE EP IMPURITY H Simvastatin EP Impurity I Methylprednisolone Acetate EP Impurity HRelated products of tetrahydrofuran
You may like
-
36394-75-9 (S)-(-)-2-Acetoxypropionly chloride 98%View Details
36394-75-9 -
36394-75-9 99%View Details
36394-75-9 -
(S)-(-)-2-Acetoxypropionyl chloride 99%View Details
36394-75-9 -
(S)-(-)-2-Acetoxypropionyl Chloride CAS 36394-75-9View Details
36394-75-9 -
(S)-(−)-2-Acetoxypropionyl chloride CAS 36394-75-9View Details
36394-75-9 -
3-(4-Chloro-butyryl) -1H-indole-5- carbonitrileView Details
276863-95-7 -
Ethyl 5-Aminobenzofuran-2- CarboxylateView Details
174775-48-5 -
2,3-dichloro-6- nitrobenzonitrileView Details
2112-23-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.