(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide

Synonym(s):FDAA;Marfey’s reagent

CAS NO.：95713-52-3
Empirical Formula: C9H9FN4O5
Molecular Weight: 272.19
MDL number: MFCD00042049
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-14 20:49:34

(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide Structural

What is (S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide?

Chemical properties

Light yellow to yellow crystal or powder

The Uses of (S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide

(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide can be used for chiral amino acid analysis.

The Uses of (S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide

FDAA was used as derivatizing reagent, in a study performed to understand unusual amino acids using reversed phase high performance liquid chromatography-electrospray ionization mass spectrometry (RPHPLC-ESI-MS).

The Uses of (S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide

N-α-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide is suitable for use for the derivatization of amino acids. glutamate and analine present in cell wall. Derivatized?D- and?L-amino acids can be resolved and quantitated by HPLC.

What are the applications of Application

Nα-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide is a reagent for the assay of enantiomeric purity of amino-acids with HPLC

General Description

N_α-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide (FDAA) is a chiral derivatizing agent (CDA), has high enantioselectivity but low sensitivity as compared to other CDAs. It is generally used to assign the stereochemistry of amino acids in trace amounts.

Biochem/physiol Actions

N-α-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide (FDAA) is a chiral derivatizing agent and is used routinely to improve the detection of underivatized amino acids in high performance liquid chromatography. Its usage is effective in separating stereoisomer.

Properties of (S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide

Melting point:	229 °C
Boiling point:	544.5±50.0 °C(Predicted)
Density	1.592±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	acetone: 10 mg/mL, clear, yellow
form	powder
pka	15.61±0.50(Predicted)
color	yellow to orange
optical activity	[α]20/D +56±2°, c = 1% in acetone
BRN	6820069

Safety information for (S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.