(S)-(+)-1-Methyl-3-pyrrolidinol

Synonym(s):(S)-(+)-3-Hydroxy-N-methylpyrrolidine

CAS NO.：104641-59-0
Empirical Formula: C5H11NO
Molecular Weight: 101.15
MDL number: MFCD03788748
EINECS: 677-547-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

(S)-(+)-1-Methyl-3-pyrrolidinol Structural

What is (S)-(+)-1-Methyl-3-pyrrolidinol?

The Uses of (S)-(+)-1-Methyl-3-pyrrolidinol

(S)-1-Methyl-3-pyrrolidinol is a useful synthetic intermediate. It is used to prepare diaryl acylaminopyrimidines as adenosine A2A antagonists. It is also used to synthesize (alkoxyamino)(pyridinylamino)pyrazinecarbonitriles as selective checkpoint kinase 1 (CHK1) inhibitors with oral antitumor activities.

Properties of (S)-(+)-1-Methyl-3-pyrrolidinol

Boiling point:	181-182 °C(lit.)
alpha	6 º (c=1%, chloroform)
Density	0.993 g/mL at 25 °C(lit.)
refractive index	n20/D 1.4660(lit.)
Flash point:	192 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	14.95±0.20(Predicted)
form	Liquid
color	Colorless to yellow to brown
optical activity	[α]20/D +6°, c = 1 in chloroform
Sensitive	Air Sensitive & Hygroscopic
BRN	4349394
CAS DataBase Reference	104641-59-0(CAS DataBase Reference)

Safety information for (S)-(+)-1-Methyl-3-pyrrolidinol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P235:Store in a well-ventilated place. Keep cool.