Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listS-1 METHANANDAMIDE

S-1 METHANANDAMIDE

S-1 METHANANDAMIDE Structural

What is S-1 METHANANDAMIDE?

Definition

ChEBI: S-1 methanandamide is a carboximidic acid.

Biological Activity

s-1 methanandamide is a cb1 receptor ligand.the cannabinoid receptor type 1 (cb1), is a g protein-coupled cannabinoid receptor located mainly in the central and peripheral nervous system. cb1 is also expressed in several cells relating to metabolism, such as muscle cells, fat cells, liver cells, and the digestive tract. the cb1 receptor has been involved in the maintenance of homeostasis in health and disease, preventing the development of excessive neuronal activity, reducing pain and other inflammatory symptoms. enhanced receptor expression has been identified in human hepatocellular carcinoma tumor samples and human prostate cancer cells [2].s-1 methanandamide was a less potent than the c-1 (r) methyl isomer when binding with cb1 receptor. s-1 methanandamide inhibited electrically evoked contractions in isolated mouse vasa deferentia with an ic50 value of 230 nm. the binding affinity of s-1 methanandamide for cb1 receptors was less than that of aea, with a ki of 175 nm for the displacement of radiolabeled cp 55,940 [1].

References

[1] abadji v, lin s, taha g, et al. (r)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability[j]. journal of medicinal chemistry, 1994, 37(12): 1889-1893.
[2] howlett a c. cannabinoid receptor signaling[m]//cannabinoids. springer berlin heidelberg, 2005: 53-79.

Properties of S-1 METHANANDAMIDE

Boiling point: 529.0±50.0 °C(Predicted)
Density  0.935±0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Soluble in DMSO;dimethyl formamide;acetonitril
form  solution in ethanol.
pka 14.51±0.10(Predicted)
color  Colorless to light yellow

Safety information for S-1 METHANANDAMIDE

Computed Descriptors for S-1 METHANANDAMIDE

Related products of tetrahydrofuran

You may like

  • 1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%
    99903-60-3
    View Details
  • 88491-46-7 98%
    88491-46-7 98%
    88491-46-7
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • 2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    1805639-70-6
    View Details
  • 1784294-80-9 98%
    1784294-80-9 98%
    1784294-80-9
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.