RS 102221 HYDROCHLORIDE
Synonym(s):4-dione hydrochloride hydrate;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulphonam ido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2
- CAS NO.:185376-97-0
- Empirical Formula: C27H31F3N4O7S
- Molecular Weight: 612.62
- MDL number: MFCD09971036
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:35
What is RS 102221 HYDROCHLORIDE?
The Uses of RS 102221 HYDROCHLORIDE
RS 102221 Hydrochloride is a selective 5-HT2C receptor antagonist.
What are the applications of Application
RS 102221 hydrochloride is a selective SR-2C antagonist
Definition
ChEBI: N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide is an aromatic ketone.
Biological Activity
Potent and selective 5-HT 2C antagonist (pK i = 8.7). Displays ~ 100-fold selectivity over the 5-HT 2A and 5-HT 2B subtypes and is > 100-fold selective over other 5-HT receptors, a- and b-adrenergic and muscarinic ACh receptors.
Properties of RS 102221 HYDROCHLORIDE
Density | 1.45 |
storage temp. | Store at RT |
solubility | DMSO: ≥20mg/mL |
form | powder |
color | white |
Safety information for RS 102221 HYDROCHLORIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for RS 102221 HYDROCHLORIDE
New Products
Pyridine 2,4,6-Tricarboxaldehyde 6-Bromo 2-Iodo Indole Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin E Tubulysin C Tubulysin F Tubulysin B Potassium HMDS (1.0 M in THF) 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Calcium Sodium Phosphosilicate IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Imeglimin Hydrochloride IH 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate 2-Chloro-3-(chloromethyl)pyridine Diethyl 2,5-di(furan-2-yl)terephthalate Benzene butanoic acid, 2-hydroxy-3-iodo-, methyl ester Methyl 4-amino-3-(4-phenylpiperazin-1-yl)benzoate 4-hydroxy-2-cyclopenten-1-oneRelated products of tetrahydrofuran
N-(5-ACETYL-2-HYDROXY-PHENYL)-METHANESULFONAMIDE
5-METHANESULPHONAMIDO-2-HYDROXYACETOPHENONE
1,3,8-TRIAZA-SPIRO[4.5]DECANE-2,4-DIONE
RS 102221 HYDROCHLORIDE
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