RP106
Synonym(s):7-n-Butyl-6-(4-hydroxyphenyl)[5H]-pyrrolo[2,3-b]pyrazine
- CAS NO.：496864-15-4
- Empirical Formula: C17H19N3O
- Molecular Weight: 281.35
- MDL number: MFCD04973542
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:51
What is RP106?
Chemical properties
Off-white Solid
The Uses of RP106
A cell-permeable pyrrolo-pyrazine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Cdk1/cyclin B, Cdk5/p35, and GSK-3 ( IC50 =700nM 1.5 uM, and 920 nM, respectively).
What are the applications of Application
Aloisine, RP106 is a selective, potent, ATP-competitive inhibitor of Cdc 2 (CDK1)/cyclin B, CDK5/p25, and GSK-3
Definition
ChEBI: 7-butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine is a member of pyrroles.
Properties of RP106
| Melting point: | 182-184°C |
| Density | 1.155 |
| storage temp. | 2-8°C |
| solubility | DMSO: >10mg/mL |
| form | Solid |
| color | Off-White to Pale Yellow |
Safety information for RP106
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for RP106
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