Rivastigmine tartrate
Synonym(s):ENA-713;Ethylmethyl-carbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester;N-Ethyl-N-methyl-carbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester tartrate;Rivastigmine tartrate;S-Rivastigmine tartrate
- CAS NO.：129101-54-8
- Empirical Formula: C18H28N2O8
- Molecular Weight: 400.42
- MDL number: MFCD03700731
- EINECS: 603-318-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-15 19:19:13
What is Rivastigmine tartrate?
Chemical properties
White to Off-White Powder
The Uses of Rivastigmine tartrate
Rivastigmine Tartrate, a cholinesterase inhibitor with IC50 of 5.5 μM, ues as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.
The Uses of Rivastigmine tartrate
A brain selective acetylcholinesterase inhibitor. Nootropic.
The Uses of Rivastigmine tartrate
Nootropic & Alzheimer’s treatment
What are the applications of Application
Rivastigmine hydrogen tartrate is a parasympathomimetic or cholinergic agent
Definition
ChEBI: A tartrate salt obtained by reaction of rivastigmine with one equivalent of (R,R)-tartaric acid. A reversible cholinesterase inhibitor.
General Description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Biochem/physiol Actions
Rivastigmine is an orally available, brain penetrant, reversible cholinesterase inhibitor that enhances cognitive function in patients with Alzheimer′s and Parkinson′s diseases. Rivastigmine inhibits both butyrylcholinesterase and acetylcholinesterase.
storage
Store at RT
Properties of Rivastigmine tartrate
| Melting point: | 123-1250C |
| alpha | D20 +4.7° (c = 5 in ethanol) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble15mg/mL, clear |
| form | powder |
| color | white to beige |
| InChI | InChI=1/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/s3 |
| CAS DataBase Reference | 129101-54-8(CAS DataBase Reference) |
Safety information for Rivastigmine tartrate
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H300:Acute toxicity,oral H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P391:Collect spillage. Hazardous to the aquatic environment P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up. |
Computed Descriptors for Rivastigmine tartrate
| InChIKey | GWHQHAUAXRMMOT-AAUFCPPMNA-N |
| SMILES | C1(=CC=CC([C@H](C)N(C)C)=C1)OC(=O)N(C)CC.[C@H](O)(C(=O)O)[C@@H](O)C(=O)O |&1:5,18,23,r| |
Rivastigmine tartrate manufacturer
Apotex Pharmachem India Pvt Ltd
1Y
Phone:+91-8022891000
product: 129101-54-8 Rivastigmine tartarate 98%
Macleods Pharmaceuticals Limited
1Y
Phone:+912266762800
product: 129101-54-8 Rivastigmine tartarate 98%
Orchid Pharma Ltd. (Formerly Known as Orchid Chemicals and Pharmaceuticals Ltd.)
1Y
Phone:+91-4428244254
product: Rivastigmine tartarate 99%
Chorus Labs Limited
1Y
Phone:+91-9640678999
Whatsapp: +91 9640678999
product: Rivastigmine tartarate 129101-54-8 98%
PSN Medicare Private Limited
1Y
Phone:+91-7702388996
Whatsapp: +91-7702388996
product: 129101-54-8 Rivastigmine tartarate 99%
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