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HomeProduct name listRivastigmine tartrate

Rivastigmine tartrate

Synonym(s):ENA-713;Ethylmethyl-carbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester;N-Ethyl-N-methyl-carbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester tartrate;Rivastigmine tartrate;S-Rivastigmine tartrate

  • CAS NO.:129101-54-8
  • Empirical Formula: C18H28N2O8
  • Molecular Weight: 400.42
  • MDL number: MFCD03700731
  • EINECS: 603-318-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-31 18:15:48
Rivastigmine tartrate Structural

What is Rivastigmine tartrate?

Chemical properties

White to Off-White Powder

The Uses of Rivastigmine tartrate

Rivastigmine Tartrate, a cholinesterase inhibitor with IC50 of 5.5 μM, ues as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.

The Uses of Rivastigmine tartrate

A brain selective acetylcholinesterase inhibitor. Nootropic.

The Uses of Rivastigmine tartrate

Nootropic & Alzheimer’s treatment

What are the applications of Application

Rivastigmine hydrogen tartrate is a parasympathomimetic or cholinergic agent

Definition

ChEBI: A tartrate salt obtained by reaction of rivastigmine with one equivalent of (R,R)-tartaric acid. A reversible cholinesterase inhibitor.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Biochem/physiol Actions

Rivastigmine is an orally available, brain penetrant, reversible cholinesterase inhibitor that enhances cognitive function in patients with Alzheimer′s and Parkinson′s diseases. Rivastigmine inhibits both butyrylcholinesterase and acetylcholinesterase.

storage

Store at RT

Properties of Rivastigmine tartrate

Melting point: 123-1250C
alpha  D20 +4.7° (c = 5 in ethanol)
storage temp.  2-8°C
solubility  H2O: soluble15mg/mL, clear
form  powder
color  white to beige
InChI InChI=1/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/s3
CAS DataBase Reference 129101-54-8(CAS DataBase Reference)

Safety information for Rivastigmine tartrate

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Environment
GHS09
GHS Hazard Statements H300:Acute toxicity,oral
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P273:Avoid release to the environment.
P391:Collect spillage. Hazardous to the aquatic environment
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405:Store locked up.

Computed Descriptors for Rivastigmine tartrate

InChIKey GWHQHAUAXRMMOT-AAUFCPPMNA-N
SMILES C1(=CC=CC([C@H](C)N(C)C)=C1)OC(=O)N(C)CC.[C@H](O)(C(=O)O)[C@@H](O)C(=O)O |&1:5,18,23,r|

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