Epinephrine bitartrate

Synonym(s):(?)-Epinephrine (+)-bitartrate salt;L-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol D-hydrogen bitartrate salt;L-Adrenaline (+)-bitartrate salt;L-Adrenaline D-hydrogentartrate;L-Epinephrine D-hydrogentartrate

CAS NO.：51-42-3
Empirical Formula: C13H19NO9
Molecular Weight: 333.29
MDL number: MFCD00035077
EINECS: 200-097-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is Epinephrine bitartrate ?

Description

Epinephrine bitartrate is the bitartrate salt form of epinephrine, a direct-acting sympathomimetic amine with bronchodilator and vasoconstricting activity. Epinephrine bitartrate acts on both alpha and beta-adrenergic receptors. By stimulating alpha-adrenergic receptors locally, this agent causes vasoconstriction and reduces vascular blood flow. Administered in the conjunctiva, epinephrine bitartrate induces vasoconstriction and decreases the production of aqueous humor mediated through alpha-adrenergic receptors. This agent relaxes bronchial smooth muscle through its beta-stimulating actions and causes bronchodilation.

Chemical properties

solid

The Uses of Epinephrine bitartrate

adrenergic agonist, bronchodilator, antiglaucoma agent

The Uses of Epinephrine bitartrate

vasodilator

What are the applications of Application

(?)-Epinephrine-(+)-bitartrate is an α,β-adrenergic receptor agonist

brand name

Bronitin (Wyeth); Medihaler-EPI (3MPharmaceuticals).

General Description

α,β-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP.

Biochem/physiol Actions

Primary Targetα,β-Adrenergic receptor agonist

Properties of Epinephrine bitartrate

Melting point:	~155 °C (dec.)
refractive index	-16.5 ° (C=2, H2O)
storage temp.	2-8°C
solubility	H₂O: soluble
form	solid
color	white
Merck	13,3650
Stability:	Stable. Incompatible with bases, oxidizing agents, iron, iron salts, copper, copper alloys.
InChI	InChI=1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)
CAS DataBase Reference	51-42-3(CAS DataBase Reference)

Safety information for Epinephrine bitartrate

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H300:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up. P501:Dispose of contents/container to..…