Rilmenidine
- CAS NO.:54187-04-1
- Empirical Formula: C10H16N2O
- Molecular Weight: 180.25
- MDL number: MFCD00865924
- EINECS: 259-021-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-30 16:33:02
What is Rilmenidine?
Description
Rilmenidine is a new antihypertensive agent with a selective alphaz-agonist/antagonist profile, reportedly useful in the management of mild to moderate hypertension. Its fmt-line indication is possible because of the clear dissociation of its antihypertensive activity from other neurophannacological effects.
Chemical properties
water soluble
Originator
Servier (France)
The Uses of Rilmenidine
I1-imidazoline binding site ligand and a2-adrenoceptor agonist, exhibits higher I1 vs. a2 selectivity than clonidine
Background
Rilmenidine has been used in trials studying the treatment of Hypertension and Chronic Kidney Disease.
Definition
ChEBI: Rilmenidine is an isourea.
brand name
Hyperium
Biological Activity
I 1 -imidazoline binding site selective ligand and α 2 -adrenoceptor agonist. Possesses greater I 1 vs α 2 selectivity than the prototypical compound, clonidine.
Metabolic pathway
In short-term rat hepatocyte cultures, oxaminozoline is metabolized and its four metabolites resulting from oxidation or hydrolysis are identified, three of which are identical to those reported in vivo. The presence of an additional minor metabolite in culture may be due to the higher metabolic rate of oxaminozoline in this model system.
Metabolism
Not Available
Properties of Rilmenidine
Melting point: | 106-107° |
Boiling point: | 355.5±9.0 °C(Predicted) |
Density | 1.45±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | H2O: 7.3 mg/mL |
form | solid |
pka | 7.88±0.50(Predicted) |
color | white |
CAS DataBase Reference | 54187-04-1(CAS DataBase Reference) |
Safety information for Rilmenidine
Computed Descriptors for Rilmenidine
Abamectin manufacturer
Varanous Labs Pvt Ltd
New Products
Tubulysin C Tubulysin D Tubulysin A Tubulysin G 2,2-diethoxyethanethioamide Tubulysin F 5-Methyl-1-indanone CYCLOBUTYLAMINE HYDROCHLORIDE 3-N-BOC-(S)-AMINO BUTYRONITRILE 4-Aminotetrahydropyran hydrochloride 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) (S)-3-Aminobutanenitrile hydrochloride 5-Nitrobarbituric acid 2-Amino-3-bromo-5-nitropyridine N-[2-(Acetylthio)-1-oxobutyl]glycine ethyl ester 5-Bromo-2-chloroisonicotinic acid methyl 2-bromobenzoate 4-chloro-2-hydroxy-5-nitropyridine 7-Methoxyquinoline-4-carboxylic acid 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrile Solifenacin Ethyl Ester Impurity / Solifenacin Acid Ethyl Ester Quetiapine S-Oxide 7-Hydroxy Metabolite Methylprednisolone Acetate EP Impurity IRelated products of tetrahydrofuran
You may like
-
54187-04-01 Rilmenidine 98%View Details
54187-04-01 -
96-10-6 Diethyl Aluminum Chloride (1.0 M in Hexane)View Details
96-10-6 -
7664-41-7View Details
7664-41-7 -
Diethyl Aluminum chloride (1.8 M in Toluene)View Details
96-10-6 -
Diethyl Aluminum Chloride (1.0 M in Heptane) 96-10-6View Details
96-10-6 -
Lithium Chloride (0.5 M in THF) 7447-41-8View Details
7447-41-8 -
7786-30-3 Magnesium Chloride (1.0 M in THF)View Details
7786-30-3 -
75-29-6 2-Chloropropane (25%M in THF)View Details
75-29-6