RHEIN-8-GLUCOSIDE

Synonym(s):8-Glucosylrhein;Glucorhein;Rhein 8-O-β-D-glucopyranoside;Rhein 8-glucopyranoside

CAS NO.：34298-86-7
Empirical Formula: C21H18O11
Molecular Weight: 446.36
MDL number: MFCD00075898
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-05 08:26:49

What is RHEIN-8-GLUCOSIDE?

The Uses of RHEIN-8-GLUCOSIDE

Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resour ce: endophytic fungi from medicinal plants.

The Uses of RHEIN-8-GLUCOSIDE

Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (R318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resource: endophytic fungi from medicinal plants.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Properties of RHEIN-8-GLUCOSIDE

Melting point:	>245°C (dec.)
Boiling point:	854.4±65.0 °C(Predicted)
Density	1.736±0.06 g/cm3(Predicted)
storage temp.	Hygroscopic, Refrigerator, under inert atmosphere
solubility	DMSO (Slightly)
pka	3.19±0.20(Predicted)
form	Solid
color	Yellow

Safety information for RHEIN-8-GLUCOSIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.