REVEROMYCIN A
- CAS NO.：134615-37-5
- Empirical Formula: C36H52O11
- Molecular Weight: 660.79
- MDL number: MFCD00912537
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is REVEROMYCIN A?
The Uses of REVEROMYCIN A
Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.
The Uses of REVEROMYCIN A
Reveromycin A is a spiroketal antibiotic inhibitor of EGF mitogenic activity. Inhibits the signal transduction of the epidermal growth factor. May be used
What are the applications of Application
Reveromycin A is a spiroketal antibiotic inhibitor of EGF mitogenic activity
Properties of REVEROMYCIN A
| Boiling point: | 849.0±65.0 °C(Predicted) |
| Density | 1.21±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMF: soluble |
| form | solid |
| pka | 4.36±0.17(Predicted) |
| color | tan |
Safety information for REVEROMYCIN A
Computed Descriptors for REVEROMYCIN A
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