ranaconitine
- CAS NO.：1360-76-5
- Empirical Formula: C32H44N2O9
- Molecular Weight: 600.7
- MDL number: MFCD11040788
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-31 18:15:48
What is ranaconitine?
Occurrence
An aconitine alkaloid, ranaconitine occurs in the ethanolic extract of the Bulgarian plant Aconitum ranunculaefolium. It forms colourless needles when crystallized from EtOH and is dextrorotatory with a specific rotation of [α]D +33.2° (c 0.5, CHCI3 ). Hydrolysis with 5% KOH furnishes ranaconine, C23H37NO7 , m.p. 107-109°C and N-acetylanthranilic acid.
The Uses of ranaconitine
Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum and displayspotential anti-inflammatory analgesic activity as well as antagonism and modulation of voltage-gated Na+ channels.
Definition
ChEBI: S-(2-aminoethyl)isothiourea is an imidothiocarbamic ester.
Properties of ranaconitine
| Melting point: | 132-134℃ |
| Boiling point: | 758.9±60.0 °C(Predicted) |
| Density | 1.39 |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml |
| form | A solid |
| pka | 12.08±0.70(Predicted) |
Safety information for ranaconitine
Computed Descriptors for ranaconitine
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