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HomeProduct name list(R)-(-)-Tetrahydrofurfurylamine

(R)-(-)-Tetrahydrofurfurylamine

Synonym(s):(R)-2-(Aminomethyl)tetrahydrofuran

(R)-(-)-Tetrahydrofurfurylamine Structural

What is (R)-(-)-Tetrahydrofurfurylamine?

Chemical properties

Colorless to light yellow liqui

The Uses of (R)-(-)-Tetrahydrofurfurylamine

(R)-(-)-Tetrahydrofurfurylamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors.

Properties of (R)-(-)-Tetrahydrofurfurylamine

Boiling point: 55 °C18 mm Hg(lit.)
alpha  -13.5 º (c-4, MeOH)
Density  0.98 g/mL at 25 °C(lit.)
refractive index  n20/D 1.455(lit.)
Flash point: 114 °F
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
form  Liquid
pka 9.47±0.29(Predicted)
Specific Gravity 0.980
color  Clear colorless
optical activity [α]20/D 12°, c = 2 in chloroform
Water Solubility  miscible
Sensitive  Hygroscopic
BRN  4652873
CAS DataBase Reference 7202-43-9(CAS DataBase Reference)

Safety information for (R)-(-)-Tetrahydrofurfurylamine

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (R)-(-)-Tetrahydrofurfurylamine

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