(R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE

Synonym(s):(R)-(+)-N,N,α-Trimethylbenzylamine

CAS NO.：19342-01-9
Empirical Formula: C10H15N
Molecular Weight: 149.23
MDL number: MFCD00008857
EINECS: 242-976-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-25 18:00:59

(R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE Structural

What is (R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE?

Chemical properties

clear colorless liquid

Chemical properties

Colorless to yellow liquid; sweet fishy aroma.

Purification Methods

The amine is mixed with aqueous 10N NaOH and extracted with toluene. The extract is washed with saturated aqueous NaCl, dried over K2CO3, and transferred to fresh K2CO3 until the solution is clear, and is filtered. The filtrate is distilled. If a short column packed with glass helices is used, the yield is reduced but a purer product is obtained. [Ingersoll Org Synth 25 89 1945, Snyder & Brewster J Am Chem Soc 71 291 4165 1949, Cope et al. J Am Chem Soc 71 3931 1949.] The (-)-picrate has m 140-141o from EtOH). The racemate [1126-71-2] has b 88-89o/16mm, 92-94o/30mm, 194-195o/760mm, d4 0.908. [Beilstein 13 III 2392.]

Properties of (R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE

Melting point:	143°C (estimate)
Boiling point:	81 °C/16 mmHg (lit.)
Density	0.908 g/mL at 25 °C (lit.)
refractive index	n20/D 1.503(lit.)
FEMA	4248 \| N,N-DIMETHYLPHENETHYLAMINE
Flash point:	148 °F
storage temp.	2-8°C
form	clear liquid
pka	8.88±0.50(Predicted)
color	Colorless to Light yellow
Odor	at 0.10 % in propylene glycol. sweet fishy ammoniacal amine
optical activity	[α]20/D +50.2°, c = 1 in methanol
JECFA Number	1613
BRN	3030178
CAS DataBase Reference	19342-01-9(CAS DataBase Reference)

Safety information for (R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.