(R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE
Synonym(s):(R)-(+)-N,N,α-Trimethylbenzylamine
- CAS NO.:19342-01-9
- Empirical Formula: C10H15N
- Molecular Weight: 149.23
- MDL number: MFCD00008857
- EINECS: 242-976-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-25 18:00:59
What is (R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE?
Chemical properties
clear colorless liquid
Chemical properties
Colorless to yellow liquid; sweet fishy aroma.
Purification Methods
The amine is mixed with aqueous 10N NaOH and extracted with toluene. The extract is washed with saturated aqueous NaCl, dried over K2CO3, and transferred to fresh K2CO3 until the solution is clear, and is filtered. The filtrate is distilled. If a short column packed with glass helices is used, the yield is reduced but a purer product is obtained. [Ingersoll Org Synth 25 89 1945, Snyder & Brewster J Am Chem Soc 71 291 4165 1949, Cope et al. J Am Chem Soc 71 3931 1949.] The (-)-picrate has m 140-141o from EtOH). The racemate [1126-71-2] has b 88-89o/16mm, 92-94o/30mm, 194-195o/760mm, d4 0.908. [Beilstein 13 III 2392.]
Properties of (R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE
Melting point: | 143°C (estimate) |
Boiling point: | 81 °C/16 mmHg (lit.) |
Density | 0.908 g/mL at 25 °C (lit.) |
refractive index | n |
FEMA | 4248 | N,N-DIMETHYLPHENETHYLAMINE |
Flash point: | 148 °F |
storage temp. | 2-8°C |
form | clear liquid |
pka | 8.88±0.50(Predicted) |
color | Colorless to Light yellow |
Odor | at 0.10 % in propylene glycol. sweet fishy ammoniacal amine |
optical activity | [α]20/D +50.2°, c = 1 in methanol |
JECFA Number | 1613 |
BRN | 3030178 |
CAS DataBase Reference | 19342-01-9(CAS DataBase Reference) |
Safety information for (R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (R)-(+)-N,N-DIMETHYL-1-PHENYLETHYLAMINE
InChIKey | BVURNMLGDQYNAF-SECBINFHSA-N |
New Products
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Boc-N-Methyl-L-phenylglycine
A,A-DIPHENYL-4-MORPHOLINEACETIC ACID, SODIUM SALT
Flunarizine dihydrochloride
PHENCYCLIDINE
(R)-(+)-N,N-DIMETHYL-1-(1-NAPHTHYL)ETHYLAMINE
METAPHIT METHANESULFONATE
PHENCYCLIDINE HYDROCHLORIDE
TRIFENMORPH
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