(R)-(-)-Epichlorohydrin
Synonym(s):(R)-(−)-2-(Chloromethyl)oxirane
- CAS NO.：51594-55-9
- Empirical Formula: C3H5ClO
- Molecular Weight: 92.52
- MDL number: MFCD00077759
- EINECS: 424-280-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 19:05:58
What is (R)-(-)-Epichlorohydrin?
Chemical properties
Colorless to light yellow liqui
The Uses of (R)-(-)-Epichlorohydrin
((R)-Epichlorohydrin) R-enantiomer of Epichlorohydrin, an important industrial chemical, is a bifunctional alkylating agent with the potential to form DNA cross-links. It is used as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels and lacquers, cement for Celluloid. Also, it is used as stabilizer.
The Uses of (R)-(-)-Epichlorohydrin
Building block for the synthesis of a key intermediate in the synthesis of stable PGI2 analogue UT-15.
Definition
ChEBI: (R)-epichlorohydrin is an epichlorohydrin. It is functionally related to a (S)-1,2-epoxypropane. It is an enantiomer of a (S)-epichlorohydrin.
Properties of (R)-(-)-Epichlorohydrin
| Melting point: | -48°C |
| Boiling point: | 114 °C(lit.) |
| alpha | 34 º (589nm, c=1, MeOH) |
| Density | 1.180 g/mL at 20 °C(lit.) |
| vapor density | 3.29 (vs air) |
| vapor pressure | 10 mm Hg ( 16.6 °C) |
| refractive index | n |
| Flash point: | 33 °C |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Liquid |
| color | Clear colorless to very pale yellow |
| explosive limit | 21% |
| optical activity | [α]20/D 34°, c = 1 in methanol |
| Water Solubility | insoluble |
| Merck | 14,3532 |
| BRN | 1420785 |
| CAS DataBase Reference | 51594-55-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Oxirane, (chloromethyl)-, (R)-(51594-55-9) |
Safety information for (R)-(-)-Epichlorohydrin
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H226:Flammable liquids H314:Skin corrosion/irritation H317:Sensitisation, Skin H350:Carcinogenicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (R)-(-)-Epichlorohydrin
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