R(+)-BAY K 8644
- CAS NO.:98791-67-4
- Empirical Formula: C16H15F3N2O4
- Molecular Weight: 356.3
- MDL number: MFCD00153768
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is R(+)-BAY K 8644?
Description
BAY-
The Uses of R(+)-BAY K 8644
(R)-(+)-Bay K 8644 is a Ca2+ channel inhibitor, whose enantiomer is a Ca2+ channel activator.
What are the applications of Application
(R)-(+)-Bay K 8644 is an L-type calcium channel protein blocker
Definition
ChEBI: (R)-Bay-K-8644 is a methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate in which the 4-position has (R)-configuration. It is an enantiomer of a (S)-Bay-K-8644.
Biological Activity
L-type Ca 2+ -channel blocker with negative inotropic and vasodilatatory effects in vivo . Enantiomer showing opposite effects to the racemate (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ) and (S)-(-)- enantiomer ((4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester ). In combination with BIX-01294, helps generate induced pluripotent stem cells (iPSCs) from mouse embryonic fibroblasts (MEFs).
storage
Store at +4°C
Properties of R(+)-BAY K 8644
storage temp. | 2-8°C |
solubility | H2O: slightly soluble |
form | solid |
color | yellow |
Safety information for R(+)-BAY K 8644
Computed Descriptors for R(+)-BAY K 8644
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