(R)-(+)-4-HYDROXY-2-PYRROLIDINONE

Synonym(s):(R)-β-Hydroxy-γ-butyrolactam

CAS NO.：22677-21-0
Empirical Formula: C4H7NO2
Molecular Weight: 101.1
MDL number: MFCD00273364
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

(R)-(+)-4-HYDROXY-2-PYRROLIDINONE Structural

What is (R)-(+)-4-HYDROXY-2-PYRROLIDINONE?

Chemical properties

white to light yellow crystal powde

The Uses of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE

(R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products.

The Uses of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE

The (R)-enantiomer intermediate in the preparation of Oxiracetam

Properties of (R)-(+)-4-HYDROXY-2-PYRROLIDINONE

Melting point:	156-160 °C
Boiling point:	363.6±35.0 °C(Predicted)
Density	1.292±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Sparingly), Methanol (Slightly), Water (Sparingly)
form	Powder
pka	13.62±0.20(Predicted)
color	White to pale yellow
optical activity	[α]23/D +43°, c = 1 in ethanol
Water Solubility	Slightly soluble in water.
BRN	1524193
CAS DataBase Reference	22677-21-0(CAS DataBase Reference)

Safety information for (R)-(+)-4-HYDROXY-2-PYRROLIDINONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.