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HomeProduct name list(R)-1-Boc-3-Hydroxypiperidine

(R)-1-Boc-3-Hydroxypiperidine

Synonym(s):(R)-tert-Butyl 3-hydroxypiperidine-1-carboxylate

(R)-1-Boc-3-Hydroxypiperidine Structural

What is (R)-1-Boc-3-Hydroxypiperidine?

Chemical properties

White powder

The Uses of (R)-1-Boc-3-Hydroxypiperidine

(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.

Properties of (R)-1-Boc-3-Hydroxypiperidine

Melting point: 43-50 °C
Boiling point: 292.3±33.0 °C(Predicted)
Density  1.107±0.06 g/cm3(Predicted)
Flash point: 104°C
storage temp.  2-8°C
solubility  soluble in Methanol
form  Low Melting Solid
pka 14.74±0.20(Predicted)
color  White to tan
optical activity [α]/D 22±3°, c = 5 in methanol
CAS DataBase Reference 143900-43-0(CAS DataBase Reference)

Safety information for (R)-1-Boc-3-Hydroxypiperidine

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.

Computed Descriptors for (R)-1-Boc-3-Hydroxypiperidine

InChIKey UIJXHKXIOCDSEB-MRVPVSSYSA-N

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