(R)-1-Boc-3-Hydroxypiperidine
Synonym(s):(R)-tert-Butyl 3-hydroxypiperidine-1-carboxylate
- CAS NO.:143900-43-0
- Empirical Formula: C10H19NO3
- Molecular Weight: 201.26
- MDL number: MFCD04115306
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-12-15 20:35:11
What is (R)-1-Boc-3-Hydroxypiperidine?
Chemical properties
White powder
The Uses of (R)-1-Boc-3-Hydroxypiperidine
(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.
Properties of (R)-1-Boc-3-Hydroxypiperidine
Melting point: | 43-50 °C |
Boiling point: | 292.3±33.0 °C(Predicted) |
Density | 1.107±0.06 g/cm3(Predicted) |
Flash point: | 104°C |
storage temp. | 2-8°C |
solubility | soluble in Methanol |
form | Low Melting Solid |
pka | 14.74±0.20(Predicted) |
color | White to tan |
optical activity | [α]/D 22±3°, c = 5 in methanol |
CAS DataBase Reference | 143900-43-0(CAS DataBase Reference) |
Safety information for (R)-1-Boc-3-Hydroxypiperidine
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for (R)-1-Boc-3-Hydroxypiperidine
InChIKey | UIJXHKXIOCDSEB-MRVPVSSYSA-N |
New Products
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(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one
Ibrutinib
(S)-Ibrutinib
Ibrutinib Dimer Impurity
2-Pyridinamine, 5-methyl-N,N-diphenyl-
Ibrutinib Impurity 9
(R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone
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