Quinine sulfate dihydrate
- CAS NO.:6119-70-6
- Empirical Formula: C20H26N2O6S
- Molecular Weight: 422.5
- MDL number: MFCD00150790
- EINECS: 639-128-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-25 16:21:11
What is Quinine sulfate dihydrate?
Chemical properties
White or almost white, crystalline powder or fine, colourless needles.
Chemical properties
Quinine sulfate is odorless and has a persistent, very bitter taste. It darkens on exposure to light. Its saturated solution is neutral or alkaline to litmus.
The Uses of Quinine sulfate dihydrate
Primary alkaloid of various species of Cinchona (Rubiaceae). Optical isomer of Quinidine. Antimalarial; muscle relaxant (skeletal).
The Uses of Quinine sulfate dihydrate
Quinine sulfate is an antimalarial agent also used as antipyreticum and in liquids (tonic etc.).
The Uses of Quinine sulfate dihydrate
Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
What are the applications of Application
Quinine hemisulfate is a Stereoisomer of quinidine
brand name
Coco-Quinine (Lilly).
Synthesis
Manufacture of quinine by extraction from cinchona bark and subsequent purification and synthesis to quinine sulfate
Properties of Quinine sulfate dihydrate
Melting point: | ~225 °C (dec.)(lit.) |
alpha | -245 º (c=2, 0.1M HCl) |
FEMA | 2977 | QUININE SULFATE |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | Soluble in a mixture of chloroform and absolute alcohol (2:1). |
form | Crystalline Powder |
color | Light yellow or beige to brown |
Odor | odorless |
Water Solubility | 0.12 g/100 mL (20 ºC) |
Sensitive | Light Sensitive |
Merck | 14,8061 |
BRN | 6113937 |
Stability: | Stable. Incompatible with strong oxidizing agents, alkalies, ammonia, strong bases, iodine. |
CAS DataBase Reference | 6119-70-6(CAS DataBase Reference) |
Safety information for Quinine sulfate dihydrate
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Quinine sulfate dihydrate
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Rivashaa Agrotech Biopharma Pvt. Ltd.
Ralington Pharma
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Alka Laboratories Pvt Ltd
Prism Industries Ltd
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