QUINACRINE MUSTARD DIHYDROCHLORIDE
Synonym(s):2-Methoxy-6-chloro-9-(4-bis[β-chloroethyl]amino-1-methylbutylamino)acridine dihydrochloride;9-[4-(Bis(2-chloroethyl)amino)-1-methylbutylamino]-6-chloro-2-methoxyacridine dihydrochloride
- CAS NO.：4213-45-0
- Empirical Formula: C23H30Cl5N3O
- Molecular Weight: 541.77
- MDL number: MFCD00043254
- EINECS: 224-140-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-11 15:28:25
What is QUINACRINE MUSTARD DIHYDROCHLORIDE?
Description
Quinacrine mustard is a fluorescent DNA-intercalating agent. It selectively binds to adenine-thymine (AT) base pairs over guanine-cytosine (GC) base pairs. Quinacrine mustard has been used to label metaphase chromosomes for karyotyping by autoradiography. It displays excitation/emission maxima of 425/480 nm, respectively.
The Uses of QUINACRINE MUSTARD DIHYDROCHLORIDE
Quinacrine mustard dihydrochloride is a fluorescent probe.
What are the applications of Application
Quinacrine mustard dihydrochloride is a fluorescent probe
Safety Profile
Questionable carcinogen with experimental neoplastigenic data. Human mutation data reported. Corrosive. When heated to decomposition it emits very toxic fumes of Cland NOx. See also QUINACRINE MUSTARD.
Properties of QUINACRINE MUSTARD DIHYDROCHLORIDE
| storage temp. | −20°C |
| solubility | Chloroform: soluble |
| form | A crystalline solid |
| Water Solubility | Water: soluble |
| BRN | 3819822 |
| CAS DataBase Reference | 4213-45-0 |
| EPA Substance Registry System | 1,4-Pentanediamine, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-, dihydrochloride (4213-45-0) |
Safety information for QUINACRINE MUSTARD DIHYDROCHLORIDE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H334:Sensitisation, respiratory H361:Reproductive toxicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for QUINACRINE MUSTARD DIHYDROCHLORIDE
| InChIKey | JETDZFFCRPFPDH-UHFFFAOYSA-N |
| SMILES | C1(NC(C)CCCN(CCCl)CCCl)C2C=CC(Cl)=CC=2N=C2C=CC(OC)=CC=12.Cl.Cl |
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