Quercetin
Synonym(s):Quercetin dihydrate;Quercetin hydrate;2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one;3,3′,4′,5,6-Pentahydroxyflavone;3,3′,4′,5,7-Pentahydroxyflavone dihydrate
- CAS NO.:117-39-5
- Empirical Formula: C15H10O7
- Molecular Weight: 302.24
- MDL number: MFCD00006828
- EINECS: 204-187-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-10 22:07:33
What is Quercetin?
Description
The name of quercetin has been used since 1857, which is derived from quercetum
(oak forest) after Quercus. Quercetin is widely found in flowers, leaves, and
fruits of various plants. Vegetables (such as onions, ginger, celery, etc.), fruits (such
as apples, strawberries, etc.), beverages (such as tea, coffee, red wine, fruit juice,
etc.), and more than 100 kinds of Chinese herbal medicines (such as Threevein
Aster, mountain white chrysanthemum, Huai rice, Apocynum, Ginkgo biloba, etc.)
contain this ingredient.
Threevein Aster is a Chinese herbal medicine and used in Jiangxi province,
China, for more than 30 years. Its plant name is three veins Mala, Compositae. It is
rich in drug sources, which can be found in Southern provinces of China. Clinical
practice proved that it has significant anti-inflammatory and expectorant effects, and
it is a good prescription for the treatment of elderly chronic bronchitis.
Description
Quercetin is a flavonoid that occurs in many plant parts including rinds, barks, clover blossoms, and ragweed pollen. Capers are an especially rich source of quercetin. In 1962, S. Rangaswami and co-workers isolated it from?Rhododendron cinnabarinum, a shrub that grows at high altitudes in Southeast Asia.
Quercetin’s bioavailability is poor, but its glycosides are readily absorbed by the body. It has been used to treat conditions ranging from eczema and inflammation to cancer and asthma. No clinical trials, however, have convincingly demonstrated its value; and it has not been approved by the US Food and Drug Administration for any use.
The Uses of Quercetin
- Quercetin has been used as an antioxidant which reversed the immunosuppressive effects of high glucose and hyperglycemic sera in type 2 diabetic patients.
- It has been used as a detoxifying phytochemical in Apis mellifera.
- It has been used as a positive control in DPPH (2,2- diphenyl-1-picryhydrazyl) radical scavenging assay. It has also been used for the preparation of calibration curve to determine total flavonoid content.
What are the applications of Application
Quercetin is a PI 3-kinase inhibitor, GPR30 activator, and apoptosis inducer
Properties of Quercetin
Melting point: | 316.5 °C |
Boiling point: | 363.28°C (rough estimate) |
Density | 1.3616 (rough estimate) |
storage temp. | room temp |
solubility | insoluble in H2O; ≥15.1 mg/mL in DMSO; ≥3.28 mg/mL in EtOH |
form | solid |
color | Yellowish |
Water Solubility | <0.1 g/100 mL at 21 ºC |
Safety information for Quercetin
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for Quercetin
InChIKey | REFJWTPEDVJJIY-UHFFFAOYSA-N |
Abamectin manufacturer
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