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HomeProduct name listPyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Synonym(s):(R)-α,α-Diphenylprolinol trimethylsilyl ether;(2R)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine

Pyrrolidine,  2-[diphenyl[(trimethylsilyl)oxy]methyl]-,  (2R)- Structural

What is Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-?

The Uses of Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether can be used as a catalyst to synthesize:

  • Glycofused tricyclic derivatives, which are used in the development of amyloid β-peptide diagnostic tools.
  • Cyclohexene carbaldehyde derivatives by reacting benzoylnitromethane with aliphatic enals.

General Description

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether is a diarylprolinol silyl ether organocatalyst.

Properties of Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Boiling point: 412.7±35.0 °C(Predicted)
Density  1.021
refractive index  n20/D1.5509
Flash point: >110℃
storage temp.  2-8°C
form  clear liquid
pka 10.01±0.10(Predicted)
color  Light orange to Yellow to Green
optical activity [α]22/D +52±5°, c = 1 in chloroform

Safety information for Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

InChIKey RSUHWMSTWSSNOW-LJQANCHMSA-N

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