PyClocK
Synonym(s):6-Chloro-benzotriazole-1-yloxy-tris-pyrrolidinophosphonium hexafluorophosphate;PyClock;TPTDP
- CAS NO.：893413-42-8
- Empirical Formula: C18H27ClF6N6OP2
- Molecular Weight: 554.8375212
- MDL number: MFCD14560589
- EINECS: 695-542-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:38
What is PyClocK?
The Uses of PyClocK
(6-Chlorobenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (or PyClock) is the 6-chloro analog of PyBOP. It can be used as an excellent coupling reagent in solution and solid-phase peptide synthesis. It is also used to suppress racemization in the synthesis of various peptide models.
Properties of PyClocK
| Melting point: | 174-180°C |
| storage temp. | 2-8°C |
| form | powder to crystal |
| color | White to Light yellow |
Safety information for PyClocK
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PyClocK
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