PTIO
Synonym(s):2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide;2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide;PTIO - CAS 18390-00-6 - Calbiochem
- CAS NO.:18390-00-6
- Empirical Formula: C13H17N2O2*
- Molecular Weight: 233.29
- MDL number: MFCD00059929
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is PTIO?
Description
PTIO is an oxidizing reagent that reacts with nitric oxide to form nitric dioxide and corresponding imino nitroxides. It can be used to assay nitric oxide production when examining nitric oxide synthase inhibitory activity.
Chemical properties
blue crystals
The Uses of PTIO
PTIO is a nitric oxide (NO) radical scavenger used to inhibit physiological effects of NO.
The Uses of PTIO
2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.
What are the applications of Application
PTIO is a nitric oxide (NO) radical scavenger used to inhibit physiological effects of NO
Synthesis Reference(s)
Journal of the American Chemical Society, 90, p. 1078, 1968 DOI: 10.1021/ja01006a053
General Description
Nitric oxide radical scavenger. Reacts with nitric oxide in a stoichiometric manner without affecting nitric oxide synthase activity. Inhibits the enhanced vascular permeability in solid tumors.
Biochem/physiol Actions
Product does not compete with ATP.
Properties of PTIO
Melting point: | approximate 86℃ |
storage temp. | 2-8°C |
solubility | soluble in Methanol |
form | Dark blue solid |
color | Blue to Dark blue |
Safety information for PTIO
Computed Descriptors for PTIO
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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