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HomeProduct name listPROSTAGLANDINS E2 METHYL ESTER

PROSTAGLANDINS E2 METHYL ESTER

PROSTAGLANDINS E2 METHYL ESTER Structural

What is PROSTAGLANDINS E2 METHYL ESTER?

Description

Prostaglandin E2 methyl ester (PGE2 methyl ester) is an analog of PGE2 with enhanced lipid solubility. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated PGs. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Affinity constants (Kd) values of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue.

What are the applications of Application

Prostaglandin E2 methyl ester is an analog of PGE2 that is believed to be involved with rapid-eye-movement sleep regulation

Properties of PROSTAGLANDINS E2 METHYL ESTER

storage temp.  −20°C
solubility  DMF: >25 mg/ml; DMSO: >30 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >150 μg/ml

Safety information for PROSTAGLANDINS E2 METHYL ESTER

Computed Descriptors for PROSTAGLANDINS E2 METHYL ESTER

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