Proctolin
- CAS NO.：100930-02-7
- Empirical Formula: C32H52N8O10
- Molecular Weight: 708.8
- MDL number: MFCD00133784
- SAFETY DATA SHEET (SDS)
What is Proctolin?
The Uses of Proctolin
Proctolin is a neuropeptide present in insects and crustaceans.
Enzyme inhibitor
This insect neuromodulator/neurotransmitter/ neurohormone (FW = 648.76 g/mol; CAS : 100930-02-7; Sequence: L-Arg-L-Tyr-L-Leu-L-Pro-L-Thr) exerts its proctolinergic action by changing the way impulses are transmitted across a synapse, often assisting a more common neurotransmitter, such as glutamate. Mode of Action: Proctolin potently stimulates visceral and skeletal muscles contraction of a number of in insects. The Drosophila melanogaster proctolin receptor (CG6986) is an orphan G-protein coupled receptor and is strongly expressed in the head, the larval hindgut, the aorta and on neuronal endings in adult hearts. Unlike classical neurotransmitters, proctolin does not change the postsynaptic conductance. It also modulates reproductive tissue, stimulating contractions of the oviducts in the American cockroach Periplaneta americana, as well as Leucophaea maderae, L. migratoria, and spermathecae in L. migratoria and Rhodnius prolixus. Proctolin also speeds up heart rate in some insects. Target(s); dipeptidyl-peptidase III, or aminoenkephalinase.
Properties of Proctolin
| storage temp. | −20°C |
Safety information for Proctolin
Computed Descriptors for Proctolin
New Products
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