Pregnenolone acetate
Synonym(s):3β-Acetoxy-5-pregnen-20-one;5-Pregnen-3β-ol-20-one acetate
- CAS NO.：1778-02-5
- Empirical Formula: C23H34O3
- Molecular Weight: 358.51
- MDL number: MFCD00003627
- EINECS: 217-212-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-27 08:37:20
What is Pregnenolone acetate?
Chemical properties
white to light yellow crystalline powder or Crystallized (methanol).
The Uses of Pregnenolone acetate
Pregnenolone acetate is an intermediate in the synthesis of progesterone. It is uses as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It has also been shown to stimulate locomotor activity and neuronal function in rats.
Definition
Pregnenolone acetate is a steroid ester. It is a pregnenolone derivative, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.
Preparation
Pregnenolone acetate can be prepared by catalytic hydrogenation (16-position double bond) of 16-Dehydropregnenolone acetate.
Properties of Pregnenolone acetate
| Melting point: | 149-152 °C(lit.) |
| Boiling point: | 430.93°C (rough estimate) |
| alpha | 22 º (c=2, C2H5OH 23 ºC) |
| Density | 1.0816 (rough estimate) |
| refractive index | 1.4700 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White |
| optical activity | [α]20/D +19°, c = 1 in ethanol |
| Merck | 14,7733 |
| BRN | 2062850 |
| CAS DataBase Reference | 1778-02-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 3Beta-acetoxypregn-5-en-20-one(1778-02-5) |
Safety information for Pregnenolone acetate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Pregnenolone acetate
| InChIKey | CRRKVZVYZQXICQ-RJJCNJEVSA-N |
New Products
6-Bromo 2-Iodo Indole Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B 2,2-diethoxyethanethioamide Tubulysin H Tubulysin F Tubulysin E 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH Fuel shell 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Imeglimin Hydrochloride IH Diethyl 2,5-di(furan-2-yl)terephthalate Methyl 4-amino-3-(pyrrolidin-1-yl)benzoate 2-(3,5-Di-tert-butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(2,4-Dibutoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Methyl 4-amino-3-(4-phenylpiperazin-1-yl)benzoate 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 5-bromo-3-iodopyridin-2-ol 5-Bromo-4,6-difluoro-2,3-dihydro-1h-indole 3-HYDROXY-8-FLUORONAPHTHALENE-1-BORONIC ACID PINACOL ESTER ((E)-3-(Dimethylamino)-2-methylacrylaldehydeRelated products of tetrahydrofuran
You may like
-
Pregnenolone acetate 98.00% CAS 1778-02-5View Details
1778-02-5 -
Pregnenolone Acetate CAS 1778-02-5View Details
1778-02-5 -
Pregnenolone acetate CAS 1778-02-5View Details
1778-02-5 -
![3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione](https://img.chemicalbook.in//ProductImageIndia/2024-09/Raw/54575d9a-6e8e-412f-ab6d-3557d5ed92e3.jpg)
3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dioneView Details
952145-70-9 -
1262243-12-8View Details
1262243-12-8 -
Sidchem 730View Details -
Sidchem BT 20View Details -
1572177-89-9View Details
1572177-89-9
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.