Pramiracetam

Synonym(s):Amacetam;N-[2-(Diisopropylamino)ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[2-[Bis(1-methylethyl)amino]ethyl]-2-oxo-1-pyrrolidineacetamide;Vinpotropil

CAS NO.：68497-62-1
Empirical Formula: C14H27N3O2
Molecular Weight: 269.38
MDL number: MFCD00867219
EINECS: 806-175-7
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 20:04:50

What is Pramiracetam?

Description

Pramiracetam as a pyrrolidones cerebral metabolism improving drug,is a kind of CNS drugs that can help improve memory, anti-forgetful , it is developed by the United States Parke-Davis pharmaceutical companies, with a strong improvement in brain function, enhancing memory, the ability to promote brain alertness, and clinical trials have proved that its activity is 6-13 times of piracetam, 3-4 times of oxiracetam, 1.25 times of aniracetam, and it is toxicity low and well tolerated, it can be used for long-term medication to improve symptoms, and delay Alzheimer-type dementia.
Clinically relevant for elderly people attention and memory disorders, benign forgetfulness of aging, senile dementia (Alzheimer's disease) prevention, enhancing memory. Pramiracetam also applies to dilate blood vessels bodybuilding health products additives.

Chemical properties

white crystals

The Uses of Pramiracetam

Pramiracetam is an inhibitor of PREP and anti-migraine agent. It is a more potent nootropic drug derived from piracetam. Pramiracetam reportedly improved cognitive deficits associated with traumatic brain injuries. It was also effective in the treatment of cognitive disorders of cerebrovascular and traumatic origins.

Background

Pramiracetam has been previously approved in some eastern European countries under the brand names Pramistar, Neupramir, and Remen. It was also previously approved in the United States with orphan drug designation . Pramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore cognitive functioning post-electroconvulsive therapy in severe depression .

What are the applications of Application

pramiracetam is an inhibitor of PREP

Definition

ChEBI: Pramiracetam is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.

brand name

Remen (ParkeDavis).

Side Effects

When taken by mouth: Piracetam is POSSIBLY SAFE when taken appropriately. Some people who take piracetam have had nausea, vomiting, weight gain, nervousness, and sleep changes.
When given by IV: Piracetam is POSSIBLY SAFE when given by IV by a healthcare professional.

Metabolism

Not Available

Properties of Pramiracetam

Melting point:	47-48°
Boiling point:	bp0.15 162-164°
Density	1.036±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
solubility	H2O: soluble10mg/mL, clear
form	powder
pka	14.76±0.46(Predicted)
color	white to beige
Merck	14,7706
InChI	InChI=1S/C14H27N3O2/c1-11(2)17(12(3)4)9-7-15-13(18)10-16-8-5-6-14(16)19/h11-12H,5-10H2,1-4H3,(H,15,18)
CAS DataBase Reference	68497-62-1(CAS DataBase Reference)

Safety information for Pramiracetam

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.