Pramiracetam
Synonym(s):Amacetam;N-[2-(Diisopropylamino)ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide;N-[2-[Bis(1-methylethyl)amino]ethyl]-2-oxo-1-pyrrolidineacetamide;Vinpotropil
- CAS NO.:68497-62-1
- Empirical Formula: C14H27N3O2
- Molecular Weight: 269.38
- MDL number: MFCD00867219
- EINECS: 806-175-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-28 18:20:31
What is Pramiracetam?
Description
Pramiracetam as a pyrrolidones cerebral metabolism improving drug,is a kind of CNS drugs that can help improve memory, anti-forgetful , it is developed by the United States Parke-Davis pharmaceutical companies, with a strong improvement in brain function, enhancing memory, the ability to promote brain alertness, and clinical trials have proved that its activity is 6-13 times of piracetam, 3-4 times of oxiracetam, 1.25 times of aniracetam, and it is toxicity low and well tolerated, it can be used for long-term medication to improve symptoms, and delay Alzheimer-type dementia.
Clinically relevant for elderly people attention and memory disorders, benign forgetfulness of aging, senile dementia (Alzheimer's disease) prevention, enhancing memory. Pramiracetam also applies to dilate blood vessels bodybuilding health products additives.
Chemical properties
white crystals
The Uses of Pramiracetam
Pramiracetam is an inhibitor of PREP and anti-migraine agent. It is a more potent nootropic drug derived from piracetam. Pramiracetam reportedly improved cognitive deficits associated with traumatic brain injuries. It was also effective in the treatment of cognitive disorders of cerebrovascular and traumatic origins.
Background
Pramiracetam has been previously approved in some eastern European countries under the brand names Pramistar, Neupramir, and Remen. It was also previously approved in the United States with orphan drug designation . Pramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore cognitive functioning post-electroconvulsive therapy in severe depression .
What are the applications of Application
pramiracetam is an inhibitor of PREP
Definition
ChEBI: Pramiracetam is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.
brand name
Remen (ParkeDavis).
Side Effects
When taken by mouth: Piracetam is POSSIBLY SAFE when taken appropriately. Some people who take piracetam have had nausea, vomiting, weight gain, nervousness, and sleep changes.
When given by IV: Piracetam is POSSIBLY SAFE when given by IV by a healthcare professional.
Metabolism
Not Available
Properties of Pramiracetam
Melting point: | 47-48° |
Boiling point: | bp0.15 162-164° |
Density | 1.036±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,2-8°C |
solubility | H2O: soluble10mg/mL, clear |
form | powder |
pka | 14.76±0.46(Predicted) |
color | white to beige |
Merck | 14,7706 |
InChI | InChI=1S/C14H27N3O2/c1-11(2)17(12(3)4)9-7-15-13(18)10-16-8-5-6-14(16)19/h11-12H,5-10H2,1-4H3,(H,15,18) |
CAS DataBase Reference | 68497-62-1(CAS DataBase Reference) |
Safety information for Pramiracetam
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Pramiracetam
InChIKey | ZULJGOSFKWFVRX-UHFFFAOYSA-N |
SMILES | N1(CC(NCCN(C(C)C)C(C)C)=O)CCCC1=O |
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