PINACRYPTOL YELLOW
Synonym(s):6-Ethoxy-1-methyl-2-(3-nitro-β-styryl)quinolinium methyl sulfate;DYRK6;FIST3;PKY;YAK1
- CAS NO.：25910-85-4
- Empirical Formula: C21H22N2O7S
- Molecular Weight: 446.47
- MDL number: MFCD00011967
- EINECS: 247-336-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is PINACRYPTOL YELLOW?
What are the applications of Application
Pinacryptol yellow is a useful dye for gel electrophoresis
General Description
HIPK3 (homeodomain-interacting protein kinase 3) is strongly expressed in the heart and muscle tissues. It is up-regulated in multidrug-resistant cells.
Biochem/physiol Actions
HIPK3 (homeodomain-interacting protein kinase 3) is a nuclear serine/threonine protein kinase and mainly controls death receptor signaling. HIPK3 is involved in the transcriptional corepression, cell differentiation, growth suppression and apoptosis. It is up-regulated in prostate cancer cells, resulting in increased resistance to Fas receptor-mediated apoptosis by disturbing association between FADD (fas-associated death domain) and caspase 8.
Properties of PINACRYPTOL YELLOW
| Melting point: | 260-262 °C(lit.) |
| storage temp. | -70°C |
| form | buffered aqueous glycerol solution |
| color | Light yellow to Amber to Dark green |
| BRN | 3881592 |
| CAS DataBase Reference | 25910-85-4(CAS DataBase Reference) |
| EPA Substance Registry System | 6-Ethoxy-1-methyl-2-(m-nitrostyryl)quinolinium methyl sulfate (25910-85-4) |
Safety information for PINACRYPTOL YELLOW
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for PINACRYPTOL YELLOW
| InChIKey | ZXQHSPWBYMLHLB-BXTVWIJMSA-M |
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