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HomeProduct name listpicromycin

picromycin

picromycin Structural

What is picromycin?

The Uses of picromycin

Pikromycin is an inhibitor of Prolyl endopeptidase.

What are the applications of Application

Pikromycin is an inhibitor of Prolyl endopeptidase

Definition

ChEBI: A macrolide antibiotic that is biosynthesised by Streptomyces venezuelae.

Enzyme inhibitor

This polyketide (FW = 525.68 g/mol; CAS 19721-56-3; bitter-tasting solid; low water solubility; soluble in benzene and acetone) from Actinomyces spp., and originally spelled pikromycin, was the first identified macrolide antibiotic. Picromycin is most likely produced as the inactive diglucoside and liberated extracellularly as the active antibiotic through the action of a b-glucosidase.

storage

+4°C

Properties of picromycin

Melting point: 169.5℃
alpha  D24 +8.2° (c = 3.5 in ethanol); D20 -33.5° (c = 2.07 in chloroform); D24 -50.2° (c = 6.3 in chloroform)
storage temp.  Store at -20°C
solubility  DMSO: soluble
form  A crystalline solid
pka 11.15±0.70(Predicted)
Boiling point: 688.1±55.0 °C(Predicted)
Density  1.14±0.1 g/cm3(Predicted)
color  White crystalline

Safety information for picromycin

Computed Descriptors for picromycin

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