PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDRO-
Synonym(s):1′-Butyl-4′-piperidinylmethyl ester;8-Amino-7-chloro-2,3-dihydro-1,4-benzodioxan-5-carboxylic acid;N-1-Butyl-4-piperinylmethyl)-3,4-dihydro-2H-[1,3] oxazino[3,2-a]indole-10-carboxamide;Piboserod
- CAS NO.：152811-62-6
- Empirical Formula: C22H31N3O2
- Molecular Weight: 369.5
- MDL number: MFCD00923681
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-04 15:51:00
What is PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDRO-?
The Uses of PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDRO-
Treatment of irritable bowel syndrome (selective 5HT4receptor antagonist).
The Uses of PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDRO-
Piboserod is a 5-HT4 receptor antagonist which has shown positive results as a Hepatitis C virus (HCV) entry inhibtor.
Biochem/physiol Actions
SB-207266 is a potent, selective, orally active and long-acting 5-HT4 antagonist in vivo.
Properties of PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDRO-
| Melting point: | 110-113° |
| Boiling point: | 570.3±35.0 °C(Predicted) |
| Density | 1.22±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 30 mg/mL; DMSO: 20 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH7.2)(1:20): 0.05 mg/mL |
| pka | 13.86±0.20(Predicted) |
| form | powder |
| color | white to beige |
Safety information for PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDRO-
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
Computed Descriptors for PIBOSEROD,2H-(1,3)OXAZINO(3,2-A)INDOLE-10-CARBOXAMIDE, N-((1-BUTYL-4-PIPERIDINYL)METHYL)-3,4-DIHYDRO-
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