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HomeProduct name listPHTHALYLSULFACETAMIDE

PHTHALYLSULFACETAMIDE

Synonym(s):2-([(4-([Acetylamino]sulfonyl)phenyl)amino]carbonyl)benzoic acid

  • CAS NO.:131-69-1
  • Empirical Formula: C16H14N2O6S
  • Molecular Weight: 362.36
  • MDL number: MFCD00020275
  • EINECS: 205-035-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
PHTHALYLSULFACETAMIDE Structural

What is PHTHALYLSULFACETAMIDE?

The Uses of PHTHALYLSULFACETAMIDE

antibacterial

Definition

ChEBI: Phthalylsulfacetamide is a member of benzamides.

brand name

Talsigel (Bristol-Myers Squibb); Thalamyd (Schering) [Name previously used: Phthalylsulphacetamide.].

Purification Methods

It is prepared by hydrolysis of N-acetamidosulfophenylpthalimide by boiling for 3hours in 15% aqueous KOH followed by treatment with Norit, filtration and acidification with AcOH. Crystallise the phthalamide from hot H2O or EtOH [Jain et al. J Indian Chem Soc 24 174 1947]. Itis antibacterial.[Beilstein 14 III 2073.]

Properties of PHTHALYLSULFACETAMIDE

Melting point: 196°
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO : ≥ 50 mg/mL (137.98 mM)
form  Solid
form  neat
color  White to off-white
EPA Substance Registry System Benzoic acid, 2-[[[4-[(acetylamino)sulfonyl]phenyl]amino]carbonyl]- (131-69-1)

Safety information for PHTHALYLSULFACETAMIDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for PHTHALYLSULFACETAMIDE

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