PHTHALYLSULFACETAMIDE
Synonym(s):2-([(4-([Acetylamino]sulfonyl)phenyl)amino]carbonyl)benzoic acid
- CAS NO.:131-69-1
- Empirical Formula: C16H14N2O6S
- Molecular Weight: 362.36
- MDL number: MFCD00020275
- EINECS: 205-035-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:06
What is PHTHALYLSULFACETAMIDE?
The Uses of PHTHALYLSULFACETAMIDE
antibacterial
Definition
ChEBI: Phthalylsulfacetamide is a member of benzamides.
brand name
Talsigel (Bristol-Myers Squibb); Thalamyd (Schering) [Name previously used: Phthalylsulphacetamide.].
Purification Methods
It is prepared by hydrolysis of N-acetamidosulfophenylpthalimide by boiling for 3hours in 15% aqueous KOH followed by treatment with Norit, filtration and acidification with AcOH. Crystallise the phthalamide from hot H2O or EtOH [Jain et al. J Indian Chem Soc 24 174 1947]. Itis antibacterial.[Beilstein 14 III 2073.]
Properties of PHTHALYLSULFACETAMIDE
Melting point: | 196° |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO : ≥ 50 mg/mL (137.98 mM) |
form | Solid |
form | neat |
color | White to off-white |
EPA Substance Registry System | Benzoic acid, 2-[[[4-[(acetylamino)sulfonyl]phenyl]amino]carbonyl]- (131-69-1) |
Safety information for PHTHALYLSULFACETAMIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PHTHALYLSULFACETAMIDE
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Ivermectin EP Impurity B Rimegepant Impurity 3 Tubulysin B Tubulysin F Tubulysin I Tubulysin H Diethyl Aluminium Cyanide (1.0 M in Toluene) 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Imeglimin Hydrochloride IH Fuel shell Calcium Sodium Phosphosilicate IH 2-Ethoxy-4-nitrobenzoic acid 4-Bromo-N,N-bis(4-iodophenyl)aniline 2-(3,5-Di-tert-butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1-Isopropyl-1H-pyrazol-5-yl)boronic acid 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 3,3-dimethyl-2-oxo-, methyl ester 2-(Tert-butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acidRelated products of tetrahydrofuran
Sulfadiazine
Phthalylsulfathiazole
o-(hydroxymethyl)benzamide
Benzoic acid, 2-(aminomethyl)- (9CI)
4-Acetamidothiophenol
N,N'-DIACETYLSULFANILAMIDE
4-AMINO-N-METHYL-BENZENESULFONAMIDE
4-Acetamidobenzenesulfonamide
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